topicCocoa Flavanols Blood Pressure Randomized Trial
claimMetS is a multifactorial condition, with its primary indicators including obesity, hypertension, dyslipidemia, insulin resistance, and hyperglycemia; i.e., a patient who possesses at least 3 of the following parameters is designated with MetS: glucose intolerance, increased levels of triglycerides, augmented waist circumference, low levels of high-density lipoprotein cholesterol (HDL-c), and hypertension [,,].
evidence level3
citationTomaru Júlia Mayumi (2026)
sourceBeyond Taste: The Impact of Chocolate on Cardiovascular and Steatotic Liver Disease Risk Factors
topicCocoa Flavanols Blood Pressure Randomized Trial
claimIt is possible to develop a close relationship with MetS, metabolic dysfunction-associated steatotic liver disease (MASLD), and CVD [,].
evidence level3
citationTomaru Júlia Mayumi (2026)
sourceBeyond Taste: The Impact of Chocolate on Cardiovascular and Steatotic Liver Disease Risk Factors
topicCocoa Flavanols Blood Pressure Randomized Trial
claimMASLD is strongly associated with various conditions, including MetS, and is characterized by the persistence of a chronic inflammatory state detrimental to the organism [,].
evidence level3
citationTomaru Júlia Mayumi (2026)
sourceBeyond Taste: The Impact of Chocolate on Cardiovascular and Steatotic Liver Disease Risk Factors
topicCocoa Flavanols Blood Pressure Randomized Trial
claim1 2 3 4 5 6 7 8 9 10 11 12 13 14 Metabolic disorders are increasing sharply due to severe modifications in lifestyle [,,,].
evidence level3
citationTomaru Júlia Mayumi (2026)
sourceBeyond Taste: The Impact of Chocolate on Cardiovascular and Steatotic Liver Disease Risk Factors
topicCocoa Flavanols Blood Pressure Randomized Trial
claimManaging risk factors through healthy eating habits and regular exercise is crucial for CVD prevention.
evidence level3
citationLee Yu Geon (2026)
sourceCardiovascular Protective Effects and Mechanisms of Action of Cacao: A Comprehensive Review
topicCocoa Flavanols Blood Pressure Randomized Trial
claimUnsaturated fatty acids found in olive oil and nuts can help prevent CVDs by regulating cholesterol metabolism.
evidence level3
citationLee Yu Geon (2026)
sourceCardiovascular Protective Effects and Mechanisms of Action of Cacao: A Comprehensive Review
topicCocoa Flavanols Blood Pressure Randomized Trial
claimAdditionally, improving the diet by reducing salt intake and limiting processed foods can also help mitigate risk factors for CVD [].
evidence level3
citationLee Yu Geon (2026)
sourceCardiovascular Protective Effects and Mechanisms of Action of Cacao: A Comprehensive Review
topicCocoa Flavanols Blood Pressure Randomized Trial
claim1 2 2 3 According to the World Health Organization, cardiovascular diseases (CVDs), including coronary artery heart disease, cerebrovascular diseases, rheumatic heart disease, and other related conditions, are the leading cause of death worldwide, with an estimated 17.9 million deaths annually [].
evidence level3
citationLee Yu Geon (2026)
sourceCardiovascular Protective Effects and Mechanisms of Action of Cacao: A Comprehensive Review