Structured evidence table for Cocoa Flavanol Eye Fatigue Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Cocoa Flavanol Eye Fatigue Randomized Trial | 1 2 3 5 6 7 8 9 More than two billion people are at risk of micronutrient deficiencies, which often involve multiple, rather than single, nutrients [,]. | 4 | Muacevic Alexander (2026) | A to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation |
| Cocoa Flavanol Eye Fatigue Randomized Trial | They are widely used to help individuals meet their daily nutrient requirements, support overall health, and address increased nutritional needs associated with pregnancy, aging, and illness. | 4 | Muacevic Alexander (2026) | A to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation |
| Cocoa Flavanol Eye Fatigue Randomized Trial | According to the National Health and Nutrition Examination Survey, MVM use in the USA increased from 35% in 1999-2000 [] to 49-52% between 2011 and 2014, with higher usage among women than men [-]. | 4 | Muacevic Alexander (2026) | A to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation |
| Cocoa Flavanol Eye Fatigue Randomized Trial | The most common deficiencies include vitamin A, folic acid, vitamin D, iron, iodine, and zinc, especially among children and women in low- and middle-income countries [-]. | 4 | Muacevic Alexander (2026) | A to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation |
| Cocoa Flavanol Eye Fatigue Randomized Trial | Emerging evidence suggests that dark chocolate (DC), rich in flavonoids, polyphenols, magnesium, and theobromine, may exert anti-inflammatory, analgesic, and neuroprotective effects. | 4 | Safari K (2025) | Dark Chocolate Mitigates Premenstrual Performance Impairments and Muscle Soreness in Female CrossFit<sup>®</sup> Athletes: Evidence from a Menstrual-Phase-Specific Trial. |
| Cocoa Flavanol Eye Fatigue Randomized Trial | Results: DC supplementation significantly improved functional performance (CINDY WOD) across all menstrual phases, with the greatest enhancement during PMS ( p p = 0.010 vs. | 4 | Safari K (2025) | Dark Chocolate Mitigates Premenstrual Performance Impairments and Muscle Soreness in Female CrossFit<sup>®</sup> Athletes: Evidence from a Menstrual-Phase-Specific Trial. |
| Cocoa Flavanol Eye Fatigue Randomized Trial | Additionally, DOMS was notably reduced in the luteal phase at 12 h, 24 h, and 72 h post-exercise in the DC condition compared to the control and placebo ( p p > 0.05). | 4 | Safari K (2025) | Dark Chocolate Mitigates Premenstrual Performance Impairments and Muscle Soreness in Female CrossFit<sup>®</sup> Athletes: Evidence from a Menstrual-Phase-Specific Trial. |
| Cocoa Flavanol Eye Fatigue Randomized Trial | Background: Hormonal fluctuations across the menstrual cycle can significantly impair physical performance, neuromuscular function, and cognitive processing in female athletes, particularly during the premenstrual phase. | 4 | Safari K (2025) | Dark Chocolate Mitigates Premenstrual Performance Impairments and Muscle Soreness in Female CrossFit<sup>®</sup> Athletes: Evidence from a Menstrual-Phase-Specific Trial. |
Source documents