Structured evidence table for Cocoa Flavanol Cognition Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Cocoa Flavanol Cognition Randomized Trial | 1 2 3 3 3 4 5 6 The characteristics of dementia syndrome are cognitive dysfunction, including memory loss, reduced executive functions, language impairment, and affected performance in daily life activities []. | 4 | Sbai Oualid (2026) | The Role of Polyphenols on Cognitive Function and Dementia Through Gut–Microbiota–Brain Axis Modulation: A Narrative Review |
| Cocoa Flavanol Cognition Randomized Trial | Notably, about 70% of older people are living in low–middle income countries [], representing a significant economic weight associated with medical costs for health systems []. | 4 | Sbai Oualid (2026) | The Role of Polyphenols on Cognitive Function and Dementia Through Gut–Microbiota–Brain Axis Modulation: A Narrative Review |
| Cocoa Flavanol Cognition Randomized Trial | In addition, it is necessary to unveil the risk factors promoting dementia in order to develop preventive strategies. | 4 | Sbai Oualid (2026) | The Role of Polyphenols on Cognitive Function and Dementia Through Gut–Microbiota–Brain Axis Modulation: A Narrative Review |
| Cocoa Flavanol Cognition Randomized Trial | Dementia affects approximately 55 million individuals worldwide, and its prevalence is expected to rise up to 131.5 million by 2050, representing a major global health challenge [,]. | 4 | Sbai Oualid (2026) | The Role of Polyphenols on Cognitive Function and Dementia Through Gut–Microbiota–Brain Axis Modulation: A Narrative Review |
| Cocoa Flavanol Cognition Randomized Trial | Alzheimer's disease (AD) is a major global neurodegenerative disorder associated with high morbidity and mortality, yet current treatments remain largely symptomatic and ineffective in halting neurodegeneration. | 4 | Zainuddin MS (2026) | Oxidative stress biomarkers and flavonoids in Alzheimer's disease: current clinical evidence and therapeutic perspectives. |
| Cocoa Flavanol Cognition Randomized Trial | Growing evidence links oxidative stress potentially being an early event in AD progression. | 4 | Zainuddin MS (2026) | Oxidative stress biomarkers and flavonoids in Alzheimer's disease: current clinical evidence and therapeutic perspectives. |
| Cocoa Flavanol Cognition Randomized Trial | This review summarizes clinical evidence of oxidative stress biomarkers in AD and examines the neuroprotective mechanisms of flavonoids against oxidative stress in vivo , together with current clinical findings. | 4 | Zainuddin MS (2026) | Oxidative stress biomarkers and flavonoids in Alzheimer's disease: current clinical evidence and therapeutic perspectives. |
Source documents