topicCitrulline Recovery Randomized Trial
claimBackground: Post-COVID-19 syndrome is associated with endothelial dysfunction (ED) and various sequelae, particularly in individuals who experienced critical illness during the acute phase, affecting lung function and the musculoskeletal system.
evidence level2
citationFernanda SM (2026)
sourceEffect of L-Citrulline Supplementation on Endothelial Function and Body Composition in Post-COVID-19 Syndrome: A Randomized Clinical Trial.
topicCitrulline Recovery Randomized Trial
claimConclusions: L-citrulline supplementation for three months decreased ICAM-1 and increased 6MWT.
evidence level2
citationFernanda SM (2026)
sourceEffect of L-Citrulline Supplementation on Endothelial Function and Body Composition in Post-COVID-19 Syndrome: A Randomized Clinical Trial.
topicCitrulline Recovery Randomized Trial
claimL-citrulline, a nonessential amino acid, has been shown to improve endothelial function, systemic inflammation, blood pressure, and physical performance.
evidence level2
citationFernanda SM (2026)
sourceEffect of L-Citrulline Supplementation on Endothelial Function and Body Composition in Post-COVID-19 Syndrome: A Randomized Clinical Trial.
topicCitrulline Recovery Randomized Trial
claimStrategies that support repeated high-intensity sprint performance are of considerable interest in competitive sprinting and team sports; however, evidence regarding acute citrulline malate (CM) supplementation during recovery intervals remains limited.
evidence level2
citationYamanaka R (2026)
sourceEffects of Acute Citrulline Malate Supplementation on Repeated 100 m Sprint Performance in Trained Sprinters: A Randomized Crossover Study.
topicCitrulline Recovery Randomized Trial
claimThis study examined the effects of acute CM supplementation on repeated 100 m sprint performance and rating of perceived exertion (RPE) in trained sprinters.
evidence level2
citationYamanaka R (2026)
sourceEffects of Acute Citrulline Malate Supplementation on Repeated 100 m Sprint Performance in Trained Sprinters: A Randomized Crossover Study.