evidence table

Citrulline Blood Pressure Randomized Trial Evidence Table

Structured evidence table for Citrulline Blood Pressure Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Citrulline Blood Pressure Randomized TrialThe primary objective of this systematic review and meta-analysis is to investigate whether L-citrulline supplementation can counteract the adverse effects of cold environments on individual blood pressure (BP), providing scientific evidence for the clinical development and application of L-citrulline as a cardiovascular protective nutritional supplement.1Luo P (2026)Effect of L-Citrulline Intake on Blood Pressure in Cold Environments: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Citrulline Blood Pressure Randomized TrialThe Cochrane Risk of Bias tool and JADAD scoring scale were used to assess risk of bias and literature quality of the included randomized controlled trials (RCTs).1Luo P (2026)Effect of L-Citrulline Intake on Blood Pressure in Cold Environments: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Citrulline Blood Pressure Randomized TrialResults indicate that L-citrulline intake significantly reduced cold-induced SBP (-9.28 mmHg [95% CI: -10.66 to -7.90], p p = 0.01).1Luo P (2026)Effect of L-Citrulline Intake on Blood Pressure in Cold Environments: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Citrulline Blood Pressure Randomized TrialA comprehensive search was conducted across four electronic databases: PubMed, Cochrane Library, Embase, and Web of Science.1Luo P (2026)Effect of L-Citrulline Intake on Blood Pressure in Cold Environments: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Citrulline Blood Pressure Randomized TrialBackground Postmenopausal women are at increased risk of developing cardiovascular, muscular, and metabolic dysfunction due to hormonal changes associated with aging.1Bahari H (2026)Citrulline supplementation in postmenopausal women: a systematic review of vascular, muscular, and metabolic effects.
Citrulline Blood Pressure Randomized TrialConclusion Citrulline supplementation may offer benefits for blood pressure regulation (up to 9 mmHg SBP reduction in some studies) in hypertensive postmenopausal women, but evidence for arterial stiffness, endothelial function, and metabolic outcomes remains inconsistent.1Bahari H (2026)Citrulline supplementation in postmenopausal women: a systematic review of vascular, muscular, and metabolic effects.
Citrulline Blood Pressure Randomized TrialCitrulline, a non-essential amino acid and precursor to nitric oxide, has gained interest as a potential dietary supplement for improving vascular health, muscle function, and metabolic parameters in this population.1Bahari H (2026)Citrulline supplementation in postmenopausal women: a systematic review of vascular, muscular, and metabolic effects.
topicCitrulline Blood Pressure Randomized Trial
claimThe primary objective of this systematic review and meta-analysis is to investigate whether L-citrulline supplementation can counteract the adverse effects of cold environments on individual blood pressure (BP), providing scientific evidence for the clinical development and application of L-citrulline as a cardiovascular protective nutritional supplement.
evidence level1
citationLuo P (2026)
sourceEffect of L-Citrulline Intake on Blood Pressure in Cold Environments: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
topicCitrulline Blood Pressure Randomized Trial
claimThe Cochrane Risk of Bias tool and JADAD scoring scale were used to assess risk of bias and literature quality of the included randomized controlled trials (RCTs).
evidence level1
citationLuo P (2026)
sourceEffect of L-Citrulline Intake on Blood Pressure in Cold Environments: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
topicCitrulline Blood Pressure Randomized Trial
claimResults indicate that L-citrulline intake significantly reduced cold-induced SBP (-9.28 mmHg [95% CI: -10.66 to -7.90], p p = 0.01).
evidence level1
citationLuo P (2026)
sourceEffect of L-Citrulline Intake on Blood Pressure in Cold Environments: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
topicCitrulline Blood Pressure Randomized Trial
claimA comprehensive search was conducted across four electronic databases: PubMed, Cochrane Library, Embase, and Web of Science.
evidence level1
citationLuo P (2026)
sourceEffect of L-Citrulline Intake on Blood Pressure in Cold Environments: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
topicCitrulline Blood Pressure Randomized Trial
claimBackground Postmenopausal women are at increased risk of developing cardiovascular, muscular, and metabolic dysfunction due to hormonal changes associated with aging.
evidence level1
citationBahari H (2026)
sourceCitrulline supplementation in postmenopausal women: a systematic review of vascular, muscular, and metabolic effects.
topicCitrulline Blood Pressure Randomized Trial
claimConclusion Citrulline supplementation may offer benefits for blood pressure regulation (up to 9 mmHg SBP reduction in some studies) in hypertensive postmenopausal women, but evidence for arterial stiffness, endothelial function, and metabolic outcomes remains inconsistent.
evidence level1
citationBahari H (2026)
sourceCitrulline supplementation in postmenopausal women: a systematic review of vascular, muscular, and metabolic effects.
topicCitrulline Blood Pressure Randomized Trial
claimCitrulline, a non-essential amino acid and precursor to nitric oxide, has gained interest as a potential dietary supplement for improving vascular health, muscle function, and metabolic parameters in this population.
evidence level1
citationBahari H (2026)
sourceCitrulline supplementation in postmenopausal women: a systematic review of vascular, muscular, and metabolic effects.

Learn next

Related evidence and supplement guides

GuideChokeberry Blood Pressure Randomized Trial: What the Evidence SaysChokeberry Blood Pressure Randomized Trial has 2 source documents in the current Migaku evidence...GuideHibiscus Blood Pressure Randomized Trial: What the Evidence SaysHibiscus Blood Pressure Randomized Trial has 2 source documents in the current Migaku evidence d...GuideGreen Coffee Blood Pressure Randomized Trial: What the Evidence SaysGreen Coffee Blood Pressure Randomized Trial has 2 source documents in the current Migaku eviden...GuideTocotrienols Blood Pressure Randomized Trial: What the Evidence SaysTocotrienols Blood Pressure Randomized Trial has 1 source documents in the current Migaku eviden...AnswerDoes Chokeberry Blood Pressure Randomized Trial work?Chokeberry Blood Pressure Randomized Trial has evidence relevant to strength of evidence and wha...AnswerIs Chokeberry Blood Pressure Randomized Trial safe?Chokeberry Blood Pressure Randomized Trial has evidence relevant to safety, limits, and clinicia...AnswerWhat does the evidence say about Chokeberry Blood Pressure Randomized Trial?Chokeberry Blood Pressure Randomized Trial has evidence relevant to benefits, uncertainty, and p...AnswerDoes Hibiscus Blood Pressure Randomized Trial work?Hibiscus Blood Pressure Randomized Trial has evidence relevant to strength of evidence and what...

Source documents

  1. Effect of L-Citrulline Intake on Blood Pressure in Cold Environments: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
  2. Citrulline supplementation in postmenopausal women: a systematic review of vascular, muscular, and metabolic effects.