topicChlorella Metabolic Health Randomized Trial
claimConversely, catalase (WMD = 22.06 U/g.Hb; 95% CI: 3.19 to 40.93) increased significantly.
evidence level1
citationMardani H (2026)
sourceBeneficial effects of Chlorella species supplementation in the general population: a GRADE-assessed systematic review and dose-response meta-analysis.
topicChlorella Metabolic Health Randomized Trial
claimWhile the evidence for BMI was rated as low, the certainty of evidence for most other outcomes was very low according to the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE).
evidence level1
citationMardani H (2026)
sourceBeneficial effects of Chlorella species supplementation in the general population: a GRADE-assessed systematic review and dose-response meta-analysis.
topicChlorella Metabolic Health Randomized Trial
claimOur findings underscore the potential of Chlorella supplementation to support metabolic health in general population; however, given the overall very low certainty of evidence based on the GRADE assessment, these results should be interpreted cautiously.
evidence level1
citationMardani H (2026)
sourceBeneficial effects of Chlorella species supplementation in the general population: a GRADE-assessed systematic review and dose-response meta-analysis.
topicChlorella Metabolic Health Randomized Trial
claimThis systematic review and meta-analysis aimed to evaluate the potential benefits of Chlorella supplementation in the general population, with a focus on its impact across a broad spectrum of health-related biomarkers and clinical parameters.
evidence level1
citationMardani H (2026)
sourceBeneficial effects of Chlorella species supplementation in the general population: a GRADE-assessed systematic review and dose-response meta-analysis.
topicChlorella Metabolic Health Randomized Trial
claimPlant-derived bioactive peptides have garnered widespread interest for their functions in managing obesity and associated metabolic disorders.
evidence level4
citationLin L (2026)
sourceA <i>Chlorella pyrenoids</i> Hexapeptide VPIIMH Alleviates Lipid Accumulation and Oxidative Stress in <i>Caenorhabditis elegans</i>: Insight from In Vitro, In Vivo, and Network Parmacology Analyses.
topicChlorella Metabolic Health Randomized Trial
claimelegans model, treatment with 0.5 mg/mL VPIIMH significantly reduced fat accumulation by 37.2% and triglyceride levels by 26.9%.
evidence level4
citationLin L (2026)
sourceA <i>Chlorella pyrenoids</i> Hexapeptide VPIIMH Alleviates Lipid Accumulation and Oxidative Stress in <i>Caenorhabditis elegans</i>: Insight from In Vitro, In Vivo, and Network Parmacology Analyses.
topicChlorella Metabolic Health Randomized Trial
claimThis study investigated the lipid-lowering activity and underlying mechanisms of VPIIMH, a hexapeptide derived from Chlorella pyrenoids , using in vitro enzymatic assays, Caenorhabditis elegans models, and network pharmacology.
evidence level4
citationLin L (2026)
sourceA <i>Chlorella pyrenoids</i> Hexapeptide VPIIMH Alleviates Lipid Accumulation and Oxidative Stress in <i>Caenorhabditis elegans</i>: Insight from In Vitro, In Vivo, and Network Parmacology Analyses.