Chlorella Lipid Profile Randomized Trial Evidence Table

Structured evidence table for Chlorella Lipid Profile Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Chlorella Lipid Profile Randomized TrialConversely, catalase (WMD = 22.06 U/g.Hb; 95% CI: 3.19 to 40.93) increased significantly.1Mardani H (2026)Beneficial effects of Chlorella species supplementation in the general population: a GRADE-assessed systematic review and dose-response meta-analysis.
Chlorella Lipid Profile Randomized TrialWhile the evidence for BMI was rated as low, the certainty of evidence for most other outcomes was very low according to the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE).1Mardani H (2026)Beneficial effects of Chlorella species supplementation in the general population: a GRADE-assessed systematic review and dose-response meta-analysis.
Chlorella Lipid Profile Randomized TrialOur findings underscore the potential of Chlorella supplementation to support metabolic health in general population; however, given the overall very low certainty of evidence based on the GRADE assessment, these results should be interpreted cautiously.1Mardani H (2026)Beneficial effects of Chlorella species supplementation in the general population: a GRADE-assessed systematic review and dose-response meta-analysis.
Chlorella Lipid Profile Randomized TrialThis systematic review and meta-analysis aimed to evaluate the potential benefits of Chlorella supplementation in the general population, with a focus on its impact across a broad spectrum of health-related biomarkers and clinical parameters.1Mardani H (2026)Beneficial effects of Chlorella species supplementation in the general population: a GRADE-assessed systematic review and dose-response meta-analysis.
Chlorella Lipid Profile Randomized TrialChlorella 5 7 8 9 10 Emerging evidence suggests that supplementation withand spirulina may be associated with improvements in metabolic parameters such as insulin sensitivity, lipid profiles, and hepatic steatosis markers while simultaneously reducing systemic inflammatory burden and oxidative stress.3Rzeski Wojciech (2026)Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
Chlorella Lipid Profile Randomized TrialWe also discuss clinical evidence, safety considerations, and translational perspectives, highlighting current knowledge gaps and future research directions necessary for the rational development of microalgae-based interventions in preventive and integrative medicine.3Rzeski Wojciech (2026)Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
Chlorella Lipid Profile Randomized Trial2 7 19 In spirulina, phycobiliproteins, particularly phycocyanin, are the dominant pigment-derived bioactives, with documented antioxidant and anti-inflammatory activity and emerging evidence for metabolic signaling effects including Nrf2 activation and the attenuation of oxidative stress in preclinical models [,,].3Rzeski Wojciech (2026)Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
Chlorella Lipid Profile Randomized TrialChlorella Arthrospira Microalgae represent a diverse group of aquatic photosynthetic microorganisms and a rich source of bioactive compounds with significant potential in functional foods, nutraceuticals, and preventive medicine.3Rzeski Wojciech (2026)Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicChlorella Lipid Profile Randomized Trial
claimConversely, catalase (WMD = 22.06 U/g.Hb; 95% CI: 3.19 to 40.93) increased significantly.
evidence level1
citationMardani H (2026)
sourceBeneficial effects of Chlorella species supplementation in the general population: a GRADE-assessed systematic review and dose-response meta-analysis.
topicChlorella Lipid Profile Randomized Trial
claimWhile the evidence for BMI was rated as low, the certainty of evidence for most other outcomes was very low according to the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE).
evidence level1
citationMardani H (2026)
sourceBeneficial effects of Chlorella species supplementation in the general population: a GRADE-assessed systematic review and dose-response meta-analysis.
topicChlorella Lipid Profile Randomized Trial
claimOur findings underscore the potential of Chlorella supplementation to support metabolic health in general population; however, given the overall very low certainty of evidence based on the GRADE assessment, these results should be interpreted cautiously.
evidence level1
citationMardani H (2026)
sourceBeneficial effects of Chlorella species supplementation in the general population: a GRADE-assessed systematic review and dose-response meta-analysis.
topicChlorella Lipid Profile Randomized Trial
claimThis systematic review and meta-analysis aimed to evaluate the potential benefits of Chlorella supplementation in the general population, with a focus on its impact across a broad spectrum of health-related biomarkers and clinical parameters.
evidence level1
citationMardani H (2026)
sourceBeneficial effects of Chlorella species supplementation in the general population: a GRADE-assessed systematic review and dose-response meta-analysis.
topicChlorella Lipid Profile Randomized Trial
claimChlorella 5 7 8 9 10 Emerging evidence suggests that supplementation withand spirulina may be associated with improvements in metabolic parameters such as insulin sensitivity, lipid profiles, and hepatic steatosis markers while simultaneously reducing systemic inflammatory burden and oxidative stress.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicChlorella Lipid Profile Randomized Trial
claimWe also discuss clinical evidence, safety considerations, and translational perspectives, highlighting current knowledge gaps and future research directions necessary for the rational development of microalgae-based interventions in preventive and integrative medicine.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicChlorella Lipid Profile Randomized Trial
claim2 7 19 In spirulina, phycobiliproteins, particularly phycocyanin, are the dominant pigment-derived bioactives, with documented antioxidant and anti-inflammatory activity and emerging evidence for metabolic signaling effects including Nrf2 activation and the attenuation of oxidative stress in preclinical models [,,].
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicChlorella Lipid Profile Randomized Trial
claimChlorella Arthrospira Microalgae represent a diverse group of aquatic photosynthetic microorganisms and a rich source of bioactive compounds with significant potential in functional foods, nutraceuticals, and preventive medicine.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence

Source documents

  1. Beneficial effects of Chlorella species supplementation in the general population: a GRADE-assessed systematic review and dose-response meta-analysis.
  2. Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence