Chlorella Blood Pressure Randomized Trial Evidence Table

Structured evidence table for Chlorella Blood Pressure Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Chlorella Blood Pressure Randomized TrialBackground/Objectives : Chlorella and Spirulina supplementation may reduce the risk of cardiometabolic diseases by better controlling blood cholesterol, triglycerides, glucose, weight, and blood pressure (BP).1Pinto-Leite M (2025)The Role of <i>Chlorella</i> and Spirulina as Adjuvants of Cardiovascular Risk Factor Control: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
Chlorella Blood Pressure Randomized TrialMethods : To gain power in assessing the impact of microalgae supplements on cardiovascular risk factors, we searched PubMed on 3 February 2023 for randomised controlled trials assessing the effects of Chlorella and Spirulina on modifiable cardiovascular risk factors.1Pinto-Leite M (2025)The Role of <i>Chlorella</i> and Spirulina as Adjuvants of Cardiovascular Risk Factor Control: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
Chlorella Blood Pressure Randomized TrialThis meta-analysis suggests Spirulina supplementation can be used as an adjuvant to control cardiometabolic risk factors, particularly for BP.1Pinto-Leite M (2025)The Role of <i>Chlorella</i> and Spirulina as Adjuvants of Cardiovascular Risk Factor Control: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
Chlorella Blood Pressure Randomized TrialHowever, the available studies are limited in size and have used different outcomes.1Pinto-Leite M (2025)The Role of <i>Chlorella</i> and Spirulina as Adjuvants of Cardiovascular Risk Factor Control: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
Chlorella Blood Pressure Randomized TrialChlorella 5 7 8 9 10 Emerging evidence suggests that supplementation withand spirulina may be associated with improvements in metabolic parameters such as insulin sensitivity, lipid profiles, and hepatic steatosis markers while simultaneously reducing systemic inflammatory burden and oxidative stress.3Rzeski Wojciech (2026)Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
Chlorella Blood Pressure Randomized TrialWe also discuss clinical evidence, safety considerations, and translational perspectives, highlighting current knowledge gaps and future research directions necessary for the rational development of microalgae-based interventions in preventive and integrative medicine.3Rzeski Wojciech (2026)Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
Chlorella Blood Pressure Randomized Trial2 7 19 In spirulina, phycobiliproteins, particularly phycocyanin, are the dominant pigment-derived bioactives, with documented antioxidant and anti-inflammatory activity and emerging evidence for metabolic signaling effects including Nrf2 activation and the attenuation of oxidative stress in preclinical models [,,].3Rzeski Wojciech (2026)Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
Chlorella Blood Pressure Randomized TrialChlorella Arthrospira Microalgae represent a diverse group of aquatic photosynthetic microorganisms and a rich source of bioactive compounds with significant potential in functional foods, nutraceuticals, and preventive medicine.3Rzeski Wojciech (2026)Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicChlorella Blood Pressure Randomized Trial
claimBackground/Objectives : Chlorella and Spirulina supplementation may reduce the risk of cardiometabolic diseases by better controlling blood cholesterol, triglycerides, glucose, weight, and blood pressure (BP).
evidence level1
citationPinto-Leite M (2025)
sourceThe Role of <i>Chlorella</i> and Spirulina as Adjuvants of Cardiovascular Risk Factor Control: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
topicChlorella Blood Pressure Randomized Trial
claimMethods : To gain power in assessing the impact of microalgae supplements on cardiovascular risk factors, we searched PubMed on 3 February 2023 for randomised controlled trials assessing the effects of Chlorella and Spirulina on modifiable cardiovascular risk factors.
evidence level1
citationPinto-Leite M (2025)
sourceThe Role of <i>Chlorella</i> and Spirulina as Adjuvants of Cardiovascular Risk Factor Control: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
topicChlorella Blood Pressure Randomized Trial
claimThis meta-analysis suggests Spirulina supplementation can be used as an adjuvant to control cardiometabolic risk factors, particularly for BP.
evidence level1
citationPinto-Leite M (2025)
sourceThe Role of <i>Chlorella</i> and Spirulina as Adjuvants of Cardiovascular Risk Factor Control: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
topicChlorella Blood Pressure Randomized Trial
claimHowever, the available studies are limited in size and have used different outcomes.
evidence level1
citationPinto-Leite M (2025)
sourceThe Role of <i>Chlorella</i> and Spirulina as Adjuvants of Cardiovascular Risk Factor Control: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
topicChlorella Blood Pressure Randomized Trial
claimChlorella 5 7 8 9 10 Emerging evidence suggests that supplementation withand spirulina may be associated with improvements in metabolic parameters such as insulin sensitivity, lipid profiles, and hepatic steatosis markers while simultaneously reducing systemic inflammatory burden and oxidative stress.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicChlorella Blood Pressure Randomized Trial
claimWe also discuss clinical evidence, safety considerations, and translational perspectives, highlighting current knowledge gaps and future research directions necessary for the rational development of microalgae-based interventions in preventive and integrative medicine.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicChlorella Blood Pressure Randomized Trial
claim2 7 19 In spirulina, phycobiliproteins, particularly phycocyanin, are the dominant pigment-derived bioactives, with documented antioxidant and anti-inflammatory activity and emerging evidence for metabolic signaling effects including Nrf2 activation and the attenuation of oxidative stress in preclinical models [,,].
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicChlorella Blood Pressure Randomized Trial
claimChlorella Arthrospira Microalgae represent a diverse group of aquatic photosynthetic microorganisms and a rich source of bioactive compounds with significant potential in functional foods, nutraceuticals, and preventive medicine.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence

Source documents

  1. The Role of <i>Chlorella</i> and Spirulina as Adjuvants of Cardiovascular Risk Factor Control: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
  2. Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence