Structured evidence table for Chicory Root Fiber Constipation Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Chicory Root Fiber Constipation Randomized Trial | Clinically, chRG-I was well-tolerated and slightly improved stool consistency compared to placebo. | 4 | Kerezoudi EN (2026) | Dietary chicory rhamnogalacturonan-I modulates gut microbiota and immune responses in healthy adults. |
| Chicory Root Fiber Constipation Randomized Trial | In an intestinal barrier challenge model, chRG-I fermentates (a pool of metabolites including SCFA and fragments of chRG-I) protected barrier integrity, modulated the cytokine milieu away from a predominantly pro-inflammatory response, as characterized by increased IL4 and IL22 and reduced IL9, IL17A, and IL21. | 4 | Kerezoudi EN (2026) | Dietary chicory rhamnogalacturonan-I modulates gut microbiota and immune responses in healthy adults. |
| Chicory Root Fiber Constipation Randomized Trial | Conclusion: Supplementation with a low dose of chRG-I is well-tolerated, beneficially modulates the gut microbiome - which can protect the intestinal barrier, and subtly enhances systemic immune readiness, suggesting that chRG-I may have benefits as a functional food ingredient. | 4 | Kerezoudi EN (2026) | Dietary chicory rhamnogalacturonan-I modulates gut microbiota and immune responses in healthy adults. |
| Chicory Root Fiber Constipation Randomized Trial | Background: Pectic rhamnogalacturonan-I (RG-I) is a dietary fiber that modulates the gut-immune axis. | 4 | Kerezoudi EN (2026) | Dietary chicory rhamnogalacturonan-I modulates gut microbiota and immune responses in healthy adults. |
| Chicory Root Fiber Constipation Randomized Trial | Background Gastrointestinal (GI) disorders associated with increased gastric acid secretion, such as gastroesophageal reflux, dyspepsia, bloating, and abdominal pain, significantly impair quality of life and present a substantial healthcare burden. | 4 | Teterovska R (2025) | Medicinal Plants in Food Supplements for Gastrointestinal Disorders: Critical Assessment of Health Claims on Gastric Acid Regulation. |
| Chicory Root Fiber Constipation Randomized Trial | Discrepancies between product information and available scientific evidence highlight regulatory and consumer protection challenges. | 4 | Teterovska R (2025) | Medicinal Plants in Food Supplements for Gastrointestinal Disorders: Critical Assessment of Health Claims on Gastric Acid Regulation. |
| Chicory Root Fiber Constipation Randomized Trial | Conventional therapies may have limited efficacy or undesirable side effects, underscoring the need for safe complementary approaches. | 4 | Teterovska R (2025) | Medicinal Plants in Food Supplements for Gastrointestinal Disorders: Critical Assessment of Health Claims on Gastric Acid Regulation. |
Source documents