Chia Seed Cardiometabolic Markers Randomized Trial Evidence Table

Structured evidence table for Chia Seed Cardiometabolic Markers Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Chia Seed Cardiometabolic Markers Randomized TrialBackground Obesity is a significant public health issue associated with various chronic diseases.1Karimi M (2024)Effects of chia seed (Salvia hispanica L.) supplementation on cardiometabolic health in overweight subjects: a systematic review and meta-analysis of RCTs.
Chia Seed Cardiometabolic Markers Randomized TrialThis review aims to comprehensively analyze the available evidence on the effects of chia seeds on cardiometabolic indices in overweight populations through a meta-analysis.1Karimi M (2024)Effects of chia seed (Salvia hispanica L.) supplementation on cardiometabolic health in overweight subjects: a systematic review and meta-analysis of RCTs.
Chia Seed Cardiometabolic Markers Randomized TrialHowever, chia seed supplementation was associated with a significant reduction in C-reactive protein (CRP) (MD: - 1.18 mg/L, p 2 , p = 0.91), but a significant reduction in waist circumference (WC) (MD: - 2.82 cm, p 2 Conclusion Chia seed supplementation does not significantly impact most lipid profile parameters and glycemic markers.1Karimi M (2024)Effects of chia seed (Salvia hispanica L.) supplementation on cardiometabolic health in overweight subjects: a systematic review and meta-analysis of RCTs.
Chia Seed Cardiometabolic Markers Randomized TrialResearch has indicated that chia seeds have the potential to improve cardiometabolic health.1Karimi M (2024)Effects of chia seed (Salvia hispanica L.) supplementation on cardiometabolic health in overweight subjects: a systematic review and meta-analysis of RCTs.
Chia Seed Cardiometabolic Markers Randomized TrialIt is often associated with hormonal imbalance, metabolic disturbances, and reproductive complications, which together contribute to an elevated risk of long-term cardiometabolic disorders.4Singnale P (2026)Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review.
Chia Seed Cardiometabolic Markers Randomized TrialTo narratively synthesize mechanistic rationale and human clinical evidence on dietary seeds and selected nutraceuticals relevant to PCOS, with emphasis on metabolic and reproductive endpoints of interest to nutrition and obstetrics/gynecology practice.4Singnale P (2026)Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review.
Chia Seed Cardiometabolic Markers Randomized TrialProposed "seed cycling" protocols have received attention, yet most clinical data are derived from mixed-seed supplementation studies or low-level evidence, such as case reports, and should be considered hypothesis-generating.4Singnale P (2026)Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review.
Chia Seed Cardiometabolic Markers Randomized TrialPolycystic ovary syndrome (PCOS) represents one of the most common endocrine disorders among women of reproductive age.4Singnale P (2026)Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review.
topicChia Seed Cardiometabolic Markers Randomized Trial
claimBackground Obesity is a significant public health issue associated with various chronic diseases.
evidence level1
citationKarimi M (2024)
sourceEffects of chia seed (Salvia hispanica L.) supplementation on cardiometabolic health in overweight subjects: a systematic review and meta-analysis of RCTs.
topicChia Seed Cardiometabolic Markers Randomized Trial
claimThis review aims to comprehensively analyze the available evidence on the effects of chia seeds on cardiometabolic indices in overweight populations through a meta-analysis.
evidence level1
citationKarimi M (2024)
sourceEffects of chia seed (Salvia hispanica L.) supplementation on cardiometabolic health in overweight subjects: a systematic review and meta-analysis of RCTs.
topicChia Seed Cardiometabolic Markers Randomized Trial
claimHowever, chia seed supplementation was associated with a significant reduction in C-reactive protein (CRP) (MD: - 1.18 mg/L, p 2 , p = 0.91), but a significant reduction in waist circumference (WC) (MD: - 2.82 cm, p 2 Conclusion Chia seed supplementation does not significantly impact most lipid profile parameters and glycemic markers.
evidence level1
citationKarimi M (2024)
sourceEffects of chia seed (Salvia hispanica L.) supplementation on cardiometabolic health in overweight subjects: a systematic review and meta-analysis of RCTs.
topicChia Seed Cardiometabolic Markers Randomized Trial
claimResearch has indicated that chia seeds have the potential to improve cardiometabolic health.
evidence level1
citationKarimi M (2024)
sourceEffects of chia seed (Salvia hispanica L.) supplementation on cardiometabolic health in overweight subjects: a systematic review and meta-analysis of RCTs.
topicChia Seed Cardiometabolic Markers Randomized Trial
claimIt is often associated with hormonal imbalance, metabolic disturbances, and reproductive complications, which together contribute to an elevated risk of long-term cardiometabolic disorders.
evidence level4
citationSingnale P (2026)
sourceRole of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review.
topicChia Seed Cardiometabolic Markers Randomized Trial
claimTo narratively synthesize mechanistic rationale and human clinical evidence on dietary seeds and selected nutraceuticals relevant to PCOS, with emphasis on metabolic and reproductive endpoints of interest to nutrition and obstetrics/gynecology practice.
evidence level4
citationSingnale P (2026)
sourceRole of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review.
topicChia Seed Cardiometabolic Markers Randomized Trial
claimProposed "seed cycling" protocols have received attention, yet most clinical data are derived from mixed-seed supplementation studies or low-level evidence, such as case reports, and should be considered hypothesis-generating.
evidence level4
citationSingnale P (2026)
sourceRole of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review.
topicChia Seed Cardiometabolic Markers Randomized Trial
claimPolycystic ovary syndrome (PCOS) represents one of the most common endocrine disorders among women of reproductive age.
evidence level4
citationSingnale P (2026)
sourceRole of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review.

Source documents

  1. Effects of chia seed (Salvia hispanica L.) supplementation on cardiometabolic health in overweight subjects: a systematic review and meta-analysis of RCTs.
  2. Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review.