exercise performance

Casein Protein Muscle Synthesis Randomized Trial Evidence Table

Structured evidence table for Casein Protein Muscle Synthesis Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Casein Protein Muscle Synthesis Randomized TrialOne of the most conspicuous manifestations of aging is the insidious reduction of skeletal muscle mass and strength, a phenomenon referred to as sarcopenia, which is intricately associated with frailty, an elevated risk of falls, and metabolic dysregulation (,).4Hao Shuai (2026)Comparative effects of pea protein vs. dairy proteins (α-lactalbumin and casein) on aminoacidemia, exercise performance, gut microbiota, hormonal responses, neurocognitive function, mood, and metabolic–inflammatory responses in older adults
Casein Protein Muscle Synthesis Randomized TrialSimultaneously, age-associated deficits in glucose metabolism, heightened low-grade inflammation, and cognitive decline further complicate health outcomes within this demographic (,).4Hao Shuai (2026)Comparative effects of pea protein vs. dairy proteins (α-lactalbumin and casein) on aminoacidemia, exercise performance, gut microbiota, hormonal responses, neurocognitive function, mood, and metabolic–inflammatory responses in older adults
Casein Protein Muscle Synthesis Randomized TrialHistorically, proteins derived from animals, such as those found in dairy, have been regarded as superior to their plant-based counterparts due to their elevated EAA content and more advantageous digestibility profiles (,).4Hao Shuai (2026)Comparative effects of pea protein vs. dairy proteins (α-lactalbumin and casein) on aminoacidemia, exercise performance, gut microbiota, hormonal responses, neurocognitive function, mood, and metabolic–inflammatory responses in older adults
Casein Protein Muscle Synthesis Randomized Trial1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 Aging is characterized by a progressive deterioration across various physiological systems, particularly in terms of skeletal muscle mass, metabolic regulation, and cognitive functionality (,).4Hao Shuai (2026)Comparative effects of pea protein vs. dairy proteins (α-lactalbumin and casein) on aminoacidemia, exercise performance, gut microbiota, hormonal responses, neurocognitive function, mood, and metabolic–inflammatory responses in older adults
Casein Protein Muscle Synthesis Randomized TrialMales exhibited a greater abundance of SMI- and SMM-associated beneficial bacteria following protein intake.4Chen Y (2025)Associations of high protein supplements with gut microbiota and skeletal muscle mass in hospitalized older people.
Casein Protein Muscle Synthesis Randomized TrialBACKGROUND/OBJECTIVE: Prolonged bed rest is highly prevalent among hospitalized older adults and markedly accelerates the loss of muscle mass and physical function.4Chen Y (2025)Associations of high protein supplements with gut microbiota and skeletal muscle mass in hospitalized older people.
Casein Protein Muscle Synthesis Randomized TrialCurrently, there are no effective interventions to counteract this decline, and the underlying mechanisms remain poorly characterized.4Chen Y (2025)Associations of high protein supplements with gut microbiota and skeletal muscle mass in hospitalized older people.
topicCasein Protein Muscle Synthesis Randomized Trial
claimOne of the most conspicuous manifestations of aging is the insidious reduction of skeletal muscle mass and strength, a phenomenon referred to as sarcopenia, which is intricately associated with frailty, an elevated risk of falls, and metabolic dysregulation (,).
evidence level4
citationHao Shuai (2026)
sourceComparative effects of pea protein vs. dairy proteins (α-lactalbumin and casein) on aminoacidemia, exercise performance, gut microbiota, hormonal responses, neurocognitive function, mood, and metabolic–inflammatory responses in older adults
topicCasein Protein Muscle Synthesis Randomized Trial
claimSimultaneously, age-associated deficits in glucose metabolism, heightened low-grade inflammation, and cognitive decline further complicate health outcomes within this demographic (,).
evidence level4
citationHao Shuai (2026)
sourceComparative effects of pea protein vs. dairy proteins (α-lactalbumin and casein) on aminoacidemia, exercise performance, gut microbiota, hormonal responses, neurocognitive function, mood, and metabolic–inflammatory responses in older adults
topicCasein Protein Muscle Synthesis Randomized Trial
claimHistorically, proteins derived from animals, such as those found in dairy, have been regarded as superior to their plant-based counterparts due to their elevated EAA content and more advantageous digestibility profiles (,).
evidence level4
citationHao Shuai (2026)
sourceComparative effects of pea protein vs. dairy proteins (α-lactalbumin and casein) on aminoacidemia, exercise performance, gut microbiota, hormonal responses, neurocognitive function, mood, and metabolic–inflammatory responses in older adults
topicCasein Protein Muscle Synthesis Randomized Trial
claim1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 Aging is characterized by a progressive deterioration across various physiological systems, particularly in terms of skeletal muscle mass, metabolic regulation, and cognitive functionality (,).
evidence level4
citationHao Shuai (2026)
sourceComparative effects of pea protein vs. dairy proteins (α-lactalbumin and casein) on aminoacidemia, exercise performance, gut microbiota, hormonal responses, neurocognitive function, mood, and metabolic–inflammatory responses in older adults
topicCasein Protein Muscle Synthesis Randomized Trial
claimMales exhibited a greater abundance of SMI- and SMM-associated beneficial bacteria following protein intake.
evidence level4
citationChen Y (2025)
sourceAssociations of high protein supplements with gut microbiota and skeletal muscle mass in hospitalized older people.
topicCasein Protein Muscle Synthesis Randomized Trial
claimBACKGROUND/OBJECTIVE: Prolonged bed rest is highly prevalent among hospitalized older adults and markedly accelerates the loss of muscle mass and physical function.
evidence level4
citationChen Y (2025)
sourceAssociations of high protein supplements with gut microbiota and skeletal muscle mass in hospitalized older people.
topicCasein Protein Muscle Synthesis Randomized Trial
claimCurrently, there are no effective interventions to counteract this decline, and the underlying mechanisms remain poorly characterized.
evidence level4
citationChen Y (2025)
sourceAssociations of high protein supplements with gut microbiota and skeletal muscle mass in hospitalized older people.

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Source documents

  1. Comparative effects of pea protein vs. dairy proteins (α-lactalbumin and casein) on aminoacidemia, exercise performance, gut microbiota, hormonal responses, neurocognitive function, mood, and metabolic–inflammatory responses in older adults
  2. Associations of high protein supplements with gut microbiota and skeletal muscle mass in hospitalized older people.