Carnitine Exercise Recovery Randomized Trial Evidence Table

Structured evidence table for Carnitine Exercise Recovery Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Carnitine Exercise Recovery Randomized TrialThe results of a prior study confirmed the protective benefits of L-carnitine due to suppression of inflammation, oxidative stress, and increased autophagy (Khedr and Werida).1Werida Rehab H. (2026)Therapeutic potential of L-carnitine in coronary artery disease: a systematic review
Carnitine Exercise Recovery Randomized TrialSeveral experimental and clinical studies have suggested that L-carnitine supplementation may confer cardiovascular benefits in CAD patients, including improved cardiac metabolism, reduced oxidative stress, attenuation of inflammatory responses, and enhanced functional outcomes (Da Silva Guimarães et al.; Dastan et al.; Lee et al.; Lee et al.; Pastoris et al.; Singhai et al.; Tarantini et al.; Xue et al.).1Werida Rehab H. (2026)Therapeutic potential of L-carnitine in coronary artery disease: a systematic review
Carnitine Exercise Recovery Randomized TrialTo our best knowledge, this is the first systematic review to address these gaps by synthesizing evidence in CAD patients across mechanistic markers such as oxidative stress, inflammatory mediators, autophagy-related markers and post-PCI myocardial-injury biomarkers together with clinical endpoints such as ventricular arrythmia, mortality and angina.1Werida Rehab H. (2026)Therapeutic potential of L-carnitine in coronary artery disease: a systematic review
Carnitine Exercise Recovery Randomized Trial2019 2019 2015 Cardiovascular disease (CVD) is the predominant cause of death worldwide, with a substantial proportion attributable to ischemic heart disease, caused by atherosclerotic coronary artery disease (CAD) (Glovaci et al.; Sarrafzadegan and Mohammadifard).1Werida Rehab H. (2026)Therapeutic potential of L-carnitine in coronary artery disease: a systematic review
Carnitine Exercise Recovery Randomized Trial1 Aging is characterized by progressive physiological decline, including loss of skeletal muscle mass and function (Sarcopenia), reduced mitochondrial efficiency, and increased oxidative stress, all of which contribute to frailty and diminished quality of life in older adults ().3Wang Xiaolan (2026)Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
Carnitine Exercise Recovery Randomized Trial1 2 3 4 5 By the age of 70, individuals may experience a 25%−30% reduction in muscle mass, which is strongly associated with impaired mobility, falls, and loss of independence ().3Wang Xiaolan (2026)Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
Carnitine Exercise Recovery Randomized TrialLow circulating glycine levels have been associated with insulin resistance, obesity, and higher cardiometabolic risk (,).3Wang Xiaolan (2026)Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
Carnitine Exercise Recovery Randomized TrialIn this review, the term “older adults” generally refers to individuals aged ≥60 or ≥65 years, consistent with definitions used by the World Health Organization and most geriatric clinical trials.3Wang Xiaolan (2026)Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
topicCarnitine Exercise Recovery Randomized Trial
claimThe results of a prior study confirmed the protective benefits of L-carnitine due to suppression of inflammation, oxidative stress, and increased autophagy (Khedr and Werida).
evidence level1
citationWerida Rehab H. (2026)
sourceTherapeutic potential of L-carnitine in coronary artery disease: a systematic review
topicCarnitine Exercise Recovery Randomized Trial
claimSeveral experimental and clinical studies have suggested that L-carnitine supplementation may confer cardiovascular benefits in CAD patients, including improved cardiac metabolism, reduced oxidative stress, attenuation of inflammatory responses, and enhanced functional outcomes (Da Silva Guimarães et al.; Dastan et al.; Lee et al.; Lee et al.; Pastoris et al.; Singhai et al.; Tarantini et al.; Xue et al.).
evidence level1
citationWerida Rehab H. (2026)
sourceTherapeutic potential of L-carnitine in coronary artery disease: a systematic review
topicCarnitine Exercise Recovery Randomized Trial
claimTo our best knowledge, this is the first systematic review to address these gaps by synthesizing evidence in CAD patients across mechanistic markers such as oxidative stress, inflammatory mediators, autophagy-related markers and post-PCI myocardial-injury biomarkers together with clinical endpoints such as ventricular arrythmia, mortality and angina.
evidence level1
citationWerida Rehab H. (2026)
sourceTherapeutic potential of L-carnitine in coronary artery disease: a systematic review
topicCarnitine Exercise Recovery Randomized Trial
claim2019 2019 2015 Cardiovascular disease (CVD) is the predominant cause of death worldwide, with a substantial proportion attributable to ischemic heart disease, caused by atherosclerotic coronary artery disease (CAD) (Glovaci et al.; Sarrafzadegan and Mohammadifard).
evidence level1
citationWerida Rehab H. (2026)
sourceTherapeutic potential of L-carnitine in coronary artery disease: a systematic review
topicCarnitine Exercise Recovery Randomized Trial
claim1 Aging is characterized by progressive physiological decline, including loss of skeletal muscle mass and function (Sarcopenia), reduced mitochondrial efficiency, and increased oxidative stress, all of which contribute to frailty and diminished quality of life in older adults ().
evidence level3
citationWang Xiaolan (2026)
sourceGlycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
topicCarnitine Exercise Recovery Randomized Trial
claim1 2 3 4 5 By the age of 70, individuals may experience a 25%−30% reduction in muscle mass, which is strongly associated with impaired mobility, falls, and loss of independence ().
evidence level3
citationWang Xiaolan (2026)
sourceGlycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
topicCarnitine Exercise Recovery Randomized Trial
claimLow circulating glycine levels have been associated with insulin resistance, obesity, and higher cardiometabolic risk (,).
evidence level3
citationWang Xiaolan (2026)
sourceGlycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
topicCarnitine Exercise Recovery Randomized Trial
claimIn this review, the term “older adults” generally refers to individuals aged ≥60 or ≥65 years, consistent with definitions used by the World Health Organization and most geriatric clinical trials.
evidence level3
citationWang Xiaolan (2026)
sourceGlycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults

Source documents

  1. Therapeutic potential of L-carnitine in coronary artery disease: a systematic review
  2. Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults