topicCaffeine Mental Fatigue Randomized Trial
claimIndividual exercise tolerance is defined as the amount of physical exertion that can be sustained before task disengagement and can be increased through appropriate training strategies [,].
evidence level4
citationStrasser Barbara (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review
topicCaffeine Mental Fatigue Randomized Trial
claimWe then integrate evidence on the ergogenic effects of various dietary interventions with existing knowledge on perception of effort, focusing on how these interventions may limit the development of fatigue during endurance exercise and thereby influence effort perception.
evidence level4
citationStrasser Barbara (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review
topicCaffeine Mental Fatigue Randomized Trial
claimSuch adjustments result in impaired time trial performance when perceived effort rises [], and improved performance when perceived effort is reduced [].
evidence level4
citationStrasser Barbara (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review
topicCaffeine Mental Fatigue Randomized Trial
claim1 2 3 4 5 1 1 Individual aerobic endurance capacity determines how long and at what intensity everyday activities, such as climbing stairs or gardening, as well as strenuous sports, including running, cycling, or swimming, can be performed [].
evidence level4
citationStrasser Barbara (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review
topicCaffeine Mental Fatigue Randomized Trial
claimAccruing mental fatigue through sustained mental activity can be specifically defined as “a gradual and cumulative process … associated with a disinclination for any effort, a general sensation of weariness, feelings of inhibition and impaired mental performance, reduced efficiency and alertness” [].
evidence level4
citationShirzad Ali (2026)
sourceDifferential effects of caffeine, acute aerobic exercise, and placebo on mental fatigue
topicCaffeine Mental Fatigue Randomized Trial
claimThough fatigue is widely accepted as a part of daily life, it has been associated with several unwanted outcomes.
evidence level4
citationShirzad Ali (2026)
sourceDifferential effects of caffeine, acute aerobic exercise, and placebo on mental fatigue
topicCaffeine Mental Fatigue Randomized Trial
claimFurther, habitual caffeine consumption has been associated with withdrawal symptoms including fatigue, headache, nausea, and depressed mood, which may manifest after 12–24 hours of caffeine deprivation [–].
evidence level4
citationShirzad Ali (2026)
sourceDifferential effects of caffeine, acute aerobic exercise, and placebo on mental fatigue
topicCaffeine Mental Fatigue Randomized Trial
claim1 2 3 4 5 8 9 10 11 12 13 Fatigue is a multidimensional concept, commonly understood as feelings of tiredness and difficulty in initiating or sustaining voluntary activity following prolonged mental or physical activity [].
evidence level4
citationShirzad Ali (2026)
sourceDifferential effects of caffeine, acute aerobic exercise, and placebo on mental fatigue