Structured evidence table for Broccoli Sprout Skin Health Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Broccoli Sprout Skin Health Randomized Trial | Almost all of the more than 80 studies addressing SF synergies provide evidence in cell lines or animal models, with many of them utilizing the gold-standard Chou–Talalay method [,] to quantify synergy, rather than merely asserting it without quantitative support. | 3 | Fahey Jed W. (2026) | Sulforaphane Synergies with Phytochemicals and Pharmaceuticals: Implications for Healthspan † |
| Broccoli Sprout Skin Health Randomized Trial | As a result, it is difficult to determine which findings are broadly reproducible, which are model-specific, and which combinations have the strongest translational rationale. | 3 | Fahey Jed W. (2026) | Sulforaphane Synergies with Phytochemicals and Pharmaceuticals: Implications for Healthspan † |
| Broccoli Sprout Skin Health Randomized Trial | Human evidence also remains limited compared with the large preclinical literature, creating an important gap between mechanistic promise and clinical applicability. | 3 | Fahey Jed W. (2026) | Sulforaphane Synergies with Phytochemicals and Pharmaceuticals: Implications for Healthspan † |
| Broccoli Sprout Skin Health Randomized Trial | 1 2 Supplemental Table S1 3 4 5 6 7 Sulforaphane (SF; 1-isothiocyanato-4-(methylsulfinyl)-butane) is generated when plant myrosinase acts on the glucosinolate glucoraphanin (GR), present at high concentration in broccoli sprouts and other cruciferous vegetables. | 3 | Fahey Jed W. (2026) | Sulforaphane Synergies with Phytochemicals and Pharmaceuticals: Implications for Healthspan † |
| Broccoli Sprout Skin Health Randomized Trial | In this narrative review, we aimed to: (i) synthesize evidence on outdoor and indoor air pollution in asthma and lung function decline; (ii) describe key modulators of pollution-related risk; (iii) evaluate diet and supplementation as effect modifiers; and (iv) outline strategies and recommendations to mitigate pollution-related asthma burden. | 4 | Carvalho PA (2026) | Air Pollution, Asthma and Diet: From Mechanisms to Prevention Strategies. |
| Broccoli Sprout Skin Health Randomized Trial | Methods A narrative synthesis was conducted based on a comprehensive PubMed literature search through 2025, integrating evidence from observational and interventional studies evaluating habitual diet and nutritional supplementation as potential modifiers of the respiratory effects of indoor and outdoor air pollution. | 4 | Carvalho PA (2026) | Air Pollution, Asthma and Diet: From Mechanisms to Prevention Strategies. |
| Broccoli Sprout Skin Health Randomized Trial | Results We synthesized human observational and interventional studies associating outdoor and indoor air pollution with asthma and lung function outcomes, highlighted major susceptibility modulators and mechanistic pathways, and appraised emerging evidence that habitual diet and nutritional supplementation might modify pollutant-related respiratory effects. | 4 | Carvalho PA (2026) | Air Pollution, Asthma and Diet: From Mechanisms to Prevention Strategies. |
| Broccoli Sprout Skin Health Randomized Trial | Background/objectives Air pollution is a major environmental determinant of asthma morbidity and lung function impairment across the life course. | 4 | Carvalho PA (2026) | Air Pollution, Asthma and Diet: From Mechanisms to Prevention Strategies. |
Source documents