Brazil Nuts Selenium Status Randomized Trial Evidence Table

Structured evidence table for Brazil Nuts Selenium Status Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Brazil Nuts Selenium Status Randomized Trial1 2 3 Metabolic impairment is characterized by an imbalance of homeostasis of the human body in favour of increased visceral fat, dyslipidaemia, compromised blood pressure and glucose/insulin regulation, and low-grade chronic inflammation [].1Godos Justyna (2022)Effect of Brazil Nuts on Selenium Status, Blood Lipids, and Biomarkers of Oxidative Stress and Inflammation: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Brazil Nuts Selenium Status Randomized TrialThe oxidative stress state exacerbated in these conditions is secondary to the release of cytokines, such as tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), leading to increased production of reactive oxygen species (ROS), which have been considered a possible pathogenic mechanism underlying cardiovascular comorbidities [].1Godos Justyna (2022)Effect of Brazil Nuts on Selenium Status, Blood Lipids, and Biomarkers of Oxidative Stress and Inflammation: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Brazil Nuts Selenium Status Randomized TrialMoreover, oxidative stress increases the oxidation of low-density lipoprotein (LDL) particles, which in turn causes injury of the endothelium, contributing to an increased risk of atherosclerosis [].1Godos Justyna (2022)Effect of Brazil Nuts on Selenium Status, Blood Lipids, and Biomarkers of Oxidative Stress and Inflammation: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Brazil Nuts Selenium Status Randomized TrialPurpose A vegan diet is associated with health benefits but may also lead to inadequate intake of essential nutrients.2Simon R (2025)Improving the selenium supply of vegans and omnivores with Brazil nut butter compared to a dietary supplement in a randomized controlled trial.
Brazil Nuts Selenium Status Randomized TrialIndependent of the dietary pattern (vegan or omnivore), Brazil nut butter as well as supplement significantly increased serum selenium and SELENOP concentrations, while there were no changes in the placebo groups.2Simon R (2025)Improving the selenium supply of vegans and omnivores with Brazil nut butter compared to a dietary supplement in a randomized controlled trial.
Brazil Nuts Selenium Status Randomized TrialConclusion Brazil nuts are a plant-based source of selenium suitable for vegans and omnivores to improve their selenium status when consumed once in a while.2Simon R (2025)Improving the selenium supply of vegans and omnivores with Brazil nut butter compared to a dietary supplement in a randomized controlled trial.
Brazil Nuts Selenium Status Randomized TrialDue to the lower selenium content in plant-based compared to animal-based foods, many vegans do not reach the recommended selenium intake in Europe.2Simon R (2025)Improving the selenium supply of vegans and omnivores with Brazil nut butter compared to a dietary supplement in a randomized controlled trial.
topicBrazil Nuts Selenium Status Randomized Trial
claim1 2 3 Metabolic impairment is characterized by an imbalance of homeostasis of the human body in favour of increased visceral fat, dyslipidaemia, compromised blood pressure and glucose/insulin regulation, and low-grade chronic inflammation [].
evidence level1
citationGodos Justyna (2022)
sourceEffect of Brazil Nuts on Selenium Status, Blood Lipids, and Biomarkers of Oxidative Stress and Inflammation: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
topicBrazil Nuts Selenium Status Randomized Trial
claimThe oxidative stress state exacerbated in these conditions is secondary to the release of cytokines, such as tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), leading to increased production of reactive oxygen species (ROS), which have been considered a possible pathogenic mechanism underlying cardiovascular comorbidities [].
evidence level1
citationGodos Justyna (2022)
sourceEffect of Brazil Nuts on Selenium Status, Blood Lipids, and Biomarkers of Oxidative Stress and Inflammation: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
topicBrazil Nuts Selenium Status Randomized Trial
claimMoreover, oxidative stress increases the oxidation of low-density lipoprotein (LDL) particles, which in turn causes injury of the endothelium, contributing to an increased risk of atherosclerosis [].
evidence level1
citationGodos Justyna (2022)
sourceEffect of Brazil Nuts on Selenium Status, Blood Lipids, and Biomarkers of Oxidative Stress and Inflammation: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
topicBrazil Nuts Selenium Status Randomized Trial
claimPurpose A vegan diet is associated with health benefits but may also lead to inadequate intake of essential nutrients.
evidence level2
citationSimon R (2025)
sourceImproving the selenium supply of vegans and omnivores with Brazil nut butter compared to a dietary supplement in a randomized controlled trial.
topicBrazil Nuts Selenium Status Randomized Trial
claimIndependent of the dietary pattern (vegan or omnivore), Brazil nut butter as well as supplement significantly increased serum selenium and SELENOP concentrations, while there were no changes in the placebo groups.
evidence level2
citationSimon R (2025)
sourceImproving the selenium supply of vegans and omnivores with Brazil nut butter compared to a dietary supplement in a randomized controlled trial.
topicBrazil Nuts Selenium Status Randomized Trial
claimConclusion Brazil nuts are a plant-based source of selenium suitable for vegans and omnivores to improve their selenium status when consumed once in a while.
evidence level2
citationSimon R (2025)
sourceImproving the selenium supply of vegans and omnivores with Brazil nut butter compared to a dietary supplement in a randomized controlled trial.
topicBrazil Nuts Selenium Status Randomized Trial
claimDue to the lower selenium content in plant-based compared to animal-based foods, many vegans do not reach the recommended selenium intake in Europe.
evidence level2
citationSimon R (2025)
sourceImproving the selenium supply of vegans and omnivores with Brazil nut butter compared to a dietary supplement in a randomized controlled trial.

Source documents

  1. Effect of Brazil Nuts on Selenium Status, Blood Lipids, and Biomarkers of Oxidative Stress and Inflammation: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
  2. Improving the selenium supply of vegans and omnivores with Brazil nut butter compared to a dietary supplement in a randomized controlled trial.