Branched-Chain Amino Acids Exercise Recovery Randomized Trial Evidence Table

Structured evidence table for Branched-Chain Amino Acids Exercise Recovery Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Branched-Chain Amino Acids Exercise Recovery Randomized TrialHowever, this can also lead to the production of BCAA-derived metabolites and potentially contribute to a state known as “anabolic resistance,” characterized by diminished muscle protein synthesis and a reduced adaptive response to training, often linked with chronic fatigue, inflammation, or dysregulated protein turnover.2Zhang Xinxin (2026)The Effect of Acute Supplementation of Branched Chain Amino Acids on Serum Metabolites During Endurance Exercise in Healthy Young Males: An Integrative Metabolomics and Correlation Analysis Based on a Randomized Crossover Study
Branched-Chain Amino Acids Exercise Recovery Randomized Trial5 7 8 5 9 Additionally, BCAAs have been associated with the attenuation of both central and peripheral fatigue [,,].2Zhang Xinxin (2026)The Effect of Acute Supplementation of Branched Chain Amino Acids on Serum Metabolites During Endurance Exercise in Healthy Young Males: An Integrative Metabolomics and Correlation Analysis Based on a Randomized Crossover Study
Branched-Chain Amino Acids Exercise Recovery Randomized TrialAfter a 3 min rest, the workload started at 80 W and increased by 40 W every 3 min until 200 W, thereafter increasing by 20W every 2 min until volitional exhaustion, with participants maintaining a cadence of ≥60 rpm.2Zhang Xinxin (2026)The Effect of Acute Supplementation of Branched Chain Amino Acids on Serum Metabolites During Endurance Exercise in Healthy Young Males: An Integrative Metabolomics and Correlation Analysis Based on a Randomized Crossover Study
Branched-Chain Amino Acids Exercise Recovery Randomized Trial1 2 3 4 2 5 6 5 Vigorous exercise can induce obvious metabolic stress, depleting energy stores and causing muscle protein damage, which underscores the importance of targeted nutritional strategies for optimal recovery [].2Zhang Xinxin (2026)The Effect of Acute Supplementation of Branched Chain Amino Acids on Serum Metabolites During Endurance Exercise in Healthy Young Males: An Integrative Metabolomics and Correlation Analysis Based on a Randomized Crossover Study
Branched-Chain Amino Acids Exercise Recovery Randomized TrialTo assess whether a low-protein vegan diet is associated with differences in recovery from exercise-induced muscle damage (EIMD) in physically active individuals.4Mendes-Netto RS (2026)Similar Muscle Recovery but Greater Soreness in Active Vegans on Low-Protein Diets Compared to High-Protein Omnivores Following Exercise-Induced Damage.
Branched-Chain Amino Acids Exercise Recovery Randomized TrialProtein intake was significantly lower in vegans (0.98 g/kg) compared to omnivores (2.14 g/kg), along with reduced intake of essential amino acids and, specifically, branched-chain amino acids (p ≤ 0.05).4Mendes-Netto RS (2026)Similar Muscle Recovery but Greater Soreness in Active Vegans on Low-Protein Diets Compared to High-Protein Omnivores Following Exercise-Induced Damage.
Branched-Chain Amino Acids Exercise Recovery Randomized TrialCK levels increased immediately after EIMD and peaked at 24 h, remaining elevated relative to baseline in both groups (p ≤ 0.05).4Mendes-Netto RS (2026)Similar Muscle Recovery but Greater Soreness in Active Vegans on Low-Protein Diets Compared to High-Protein Omnivores Following Exercise-Induced Damage.
Branched-Chain Amino Acids Exercise Recovery Randomized TrialPhysically active vegans (n = 7) and omnivores (n = 7) underwent a lower-body muscle damage protocol consisting of five sets of repetitions to failure using the Smith machine squat and leg press at 85% of one-repetition maximum (1RM).4Mendes-Netto RS (2026)Similar Muscle Recovery but Greater Soreness in Active Vegans on Low-Protein Diets Compared to High-Protein Omnivores Following Exercise-Induced Damage.
topicBranched-Chain Amino Acids Exercise Recovery Randomized Trial
claimHowever, this can also lead to the production of BCAA-derived metabolites and potentially contribute to a state known as “anabolic resistance,” characterized by diminished muscle protein synthesis and a reduced adaptive response to training, often linked with chronic fatigue, inflammation, or dysregulated protein turnover.
evidence level2
citationZhang Xinxin (2026)
sourceThe Effect of Acute Supplementation of Branched Chain Amino Acids on Serum Metabolites During Endurance Exercise in Healthy Young Males: An Integrative Metabolomics and Correlation Analysis Based on a Randomized Crossover Study
topicBranched-Chain Amino Acids Exercise Recovery Randomized Trial
claim5 7 8 5 9 Additionally, BCAAs have been associated with the attenuation of both central and peripheral fatigue [,,].
evidence level2
citationZhang Xinxin (2026)
sourceThe Effect of Acute Supplementation of Branched Chain Amino Acids on Serum Metabolites During Endurance Exercise in Healthy Young Males: An Integrative Metabolomics and Correlation Analysis Based on a Randomized Crossover Study
topicBranched-Chain Amino Acids Exercise Recovery Randomized Trial
claimAfter a 3 min rest, the workload started at 80 W and increased by 40 W every 3 min until 200 W, thereafter increasing by 20W every 2 min until volitional exhaustion, with participants maintaining a cadence of ≥60 rpm.
evidence level2
citationZhang Xinxin (2026)
sourceThe Effect of Acute Supplementation of Branched Chain Amino Acids on Serum Metabolites During Endurance Exercise in Healthy Young Males: An Integrative Metabolomics and Correlation Analysis Based on a Randomized Crossover Study
topicBranched-Chain Amino Acids Exercise Recovery Randomized Trial
claim1 2 3 4 2 5 6 5 Vigorous exercise can induce obvious metabolic stress, depleting energy stores and causing muscle protein damage, which underscores the importance of targeted nutritional strategies for optimal recovery [].
evidence level2
citationZhang Xinxin (2026)
sourceThe Effect of Acute Supplementation of Branched Chain Amino Acids on Serum Metabolites During Endurance Exercise in Healthy Young Males: An Integrative Metabolomics and Correlation Analysis Based on a Randomized Crossover Study
topicBranched-Chain Amino Acids Exercise Recovery Randomized Trial
claimTo assess whether a low-protein vegan diet is associated with differences in recovery from exercise-induced muscle damage (EIMD) in physically active individuals.
evidence level4
citationMendes-Netto RS (2026)
sourceSimilar Muscle Recovery but Greater Soreness in Active Vegans on Low-Protein Diets Compared to High-Protein Omnivores Following Exercise-Induced Damage.
topicBranched-Chain Amino Acids Exercise Recovery Randomized Trial
claimProtein intake was significantly lower in vegans (0.98 g/kg) compared to omnivores (2.14 g/kg), along with reduced intake of essential amino acids and, specifically, branched-chain amino acids (p ≤ 0.05).
evidence level4
citationMendes-Netto RS (2026)
sourceSimilar Muscle Recovery but Greater Soreness in Active Vegans on Low-Protein Diets Compared to High-Protein Omnivores Following Exercise-Induced Damage.
topicBranched-Chain Amino Acids Exercise Recovery Randomized Trial
claimCK levels increased immediately after EIMD and peaked at 24 h, remaining elevated relative to baseline in both groups (p ≤ 0.05).
evidence level4
citationMendes-Netto RS (2026)
sourceSimilar Muscle Recovery but Greater Soreness in Active Vegans on Low-Protein Diets Compared to High-Protein Omnivores Following Exercise-Induced Damage.
topicBranched-Chain Amino Acids Exercise Recovery Randomized Trial
claimPhysically active vegans (n = 7) and omnivores (n = 7) underwent a lower-body muscle damage protocol consisting of five sets of repetitions to failure using the Smith machine squat and leg press at 85% of one-repetition maximum (1RM).
evidence level4
citationMendes-Netto RS (2026)
sourceSimilar Muscle Recovery but Greater Soreness in Active Vegans on Low-Protein Diets Compared to High-Protein Omnivores Following Exercise-Induced Damage.

Source documents

  1. The Effect of Acute Supplementation of Branched Chain Amino Acids on Serum Metabolites During Endurance Exercise in Healthy Young Males: An Integrative Metabolomics and Correlation Analysis Based on a Randomized Crossover Study
  2. Similar Muscle Recovery but Greater Soreness in Active Vegans on Low-Protein Diets Compared to High-Protein Omnivores Following Exercise-Induced Damage.