topicBranched-Chain Amino Acids Exercise Recovery Meta-Analysis
claimResults Acute BCAA supplementation was significantly associated with enhanced fat oxidation and attenuated post-exercise increases in plasma ammonia, creatine kinase, and lactate dehydrogenase, suggesting the potential improvements in energy supply and membrane stability.
evidence level2
citationZhang X (2026)
sourceThe Effect of Acute Supplementation of Branched Chain Amino Acids on Serum Metabolites During Endurance Exercise in Healthy Young Males: An Integrative Metabolomics and Correlation Analysis Based on a Randomized Crossover Study.
topicBranched-Chain Amino Acids Exercise Recovery Meta-Analysis
claimCorrelation analysis further showed that changes in metabolite profiles were strongly associated with biochemical outcomes, particularly linking enhanced fat oxidation and ammonia clearance with BCAA intake.
evidence level2
citationZhang X (2026)
sourceThe Effect of Acute Supplementation of Branched Chain Amino Acids on Serum Metabolites During Endurance Exercise in Healthy Young Males: An Integrative Metabolomics and Correlation Analysis Based on a Randomized Crossover Study.
topicBranched-Chain Amino Acids Exercise Recovery Meta-Analysis
claimBackground Branched-chain amino acids (BCAAs) are popular as sports supplements due to their ability to enhance performance and recovery.
evidence level2
citationZhang X (2026)
sourceThe Effect of Acute Supplementation of Branched Chain Amino Acids on Serum Metabolites During Endurance Exercise in Healthy Young Males: An Integrative Metabolomics and Correlation Analysis Based on a Randomized Crossover Study.
topicBranched-Chain Amino Acids Exercise Recovery Meta-Analysis
claimHowever, the full spectrum of metabolic alterations triggered by acute supplementation with BCAAs in conjunction with exercise remains incompletely understood.
evidence level2
citationZhang X (2026)
sourceThe Effect of Acute Supplementation of Branched Chain Amino Acids on Serum Metabolites During Endurance Exercise in Healthy Young Males: An Integrative Metabolomics and Correlation Analysis Based on a Randomized Crossover Study.
topicBranched-Chain Amino Acids Exercise Recovery Meta-Analysis
claimOf particular importance is myosteatosis, pathological lipid infiltration of skeletal muscle, which is increasingly implicated in impaired mobility, heightened morbidity, and poor survival, and is associated with adiposity, metabolic derangement, and mortality largely independent of muscle quantity ().
evidence level3
citationAl Turki Maha (2026)
sourceBeyond body mass index: phenotypic and circulating biomarkers for the identification and characterization of sarcopenic obesity
topicBranched-Chain Amino Acids Exercise Recovery Meta-Analysis
claimThe present review is distinct in being clinically and nutritionally oriented rather than technological or purely quantitative; in foregrounding the translational barriers that have impeded biomarker adoption and the muscle-preservation imperative of the GLP-1 era; and in explicitly separating SO-specific evidence from findings extrapolated from sarcopenia or obesity ().
evidence level3
citationAl Turki Maha (2026)
sourceBeyond body mass index: phenotypic and circulating biomarkers for the identification and characterization of sarcopenic obesity
topicBranched-Chain Amino Acids Exercise Recovery Meta-Analysis
claimRather than an operational, validated algorithm, we offer a conceptual scaffold intended to structure hypothesis-driven research and to identify individuals at risk of developing SO.
evidence level3
citationAl Turki Maha (2026)
sourceBeyond body mass index: phenotypic and circulating biomarkers for the identification and characterization of sarcopenic obesity
topicBranched-Chain Amino Acids Exercise Recovery Meta-Analysis
claim1 2 2 3 The convergence of two global trends, population aging and the rising prevalence of obesity, has produced a clinically important but frequently overlooked phenotype in which excess adiposity coexists with progressive skeletal muscle depletion.
evidence level3
citationAl Turki Maha (2026)
sourceBeyond body mass index: phenotypic and circulating biomarkers for the identification and characterization of sarcopenic obesity
topicBranched-Chain Amino Acids Exercise Recovery Meta-Analysis
claimThe aim was to provide experimental evidence for improving the efficacy and rational use of whey protein supplementation.
evidence level4
citationXin Zekun (2026)
sourceExercise-Induced Dehydration Limits the Effectiveness of Post-Exercise Whey Protein Supplementation in Healthy Young Men
topicBranched-Chain Amino Acids Exercise Recovery Meta-Analysis
claimSerum concentrations of total amino acids, BCAAs, leucine, isoleucine, valine, and glutamine increased over time following whey protein ingestion (all time effects,< 0.001).
evidence level4
citationXin Zekun (2026)
sourceExercise-Induced Dehydration Limits the Effectiveness of Post-Exercise Whey Protein Supplementation in Healthy Young Men
topicBranched-Chain Amino Acids Exercise Recovery Meta-Analysis
claim18 The primary finding was that exercise-induced hypohydration of approximately 2.2% of BM significantly attenuated the early post-prandial serum amino acid response following whey protein ingestion, as reflected by lower concentrations at 60 min and reduced 0–120 min %iAUC for total amino acids, BCAAs, isoleucine, and glutamine.
evidence level4
citationXin Zekun (2026)
sourceExercise-Induced Dehydration Limits the Effectiveness of Post-Exercise Whey Protein Supplementation in Healthy Young Men
topicBranched-Chain Amino Acids Exercise Recovery Meta-Analysis
claim1 2 3 4 2 3 4 5 6 7 Whey protein is widely utilized for post-exercise skeletal muscle remodeling [,,,] and training recovery [,,,], owing to its complete profile of essential amino acids, its exceptionally high concentration of branched-chain amino acids (BCAAs), and its rapid digestibility and absorbability.
evidence level4
citationXin Zekun (2026)
sourceExercise-Induced Dehydration Limits the Effectiveness of Post-Exercise Whey Protein Supplementation in Healthy Young Men