Boswellia Knee Pain Randomized Trial Evidence Table

Structured evidence table for Boswellia Knee Pain Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Boswellia Knee Pain Randomized TrialNutritional supplements are increasingly used for KOA due to their low risk, but direct comparative evidence on their efficacy and safety remains scarce.1Zhang Y (2025)Comparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis.
Boswellia Knee Pain Randomized TrialBackground : Knee osteoarthritis (KOA) is a prevalent degenerative joint disease that can greatly affect quality of life in middle-aged and elderly individuals.1Zhang Y (2025)Comparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis.
Boswellia Knee Pain Randomized TrialIt causes chronic pain, reduced mobility, and disability, affecting 607 million individuals worldwide, with nearly 46.6 million new cases annually [].4Muacevic Alexander (2026)Evidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion
Boswellia Knee Pain Randomized Trial11 12 13 14 15 11 15 HLA-DRB1 HLA-DQB1 Genetic polymorphisms in sterol regulatory element-binding protein 2 (rs2228314) [], interleukin-6 (rs1800795) [], and resistin (RETN) [] in Indian and Pakistani cohorts and growth differentiation factor 5 (rs143383) [],, andin Thai populations [] are linked to OA risk.4Muacevic Alexander (2026)Evidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion
Boswellia Knee Pain Randomized TrialNeed for expert opinion Despite growing clinical and mechanistic evidence for collagen supplementation in OA, several gaps and challenges remain in translating this knowledge into clinical practice, especially in the Indian subcontinent and Southeast Asia.4Muacevic Alexander (2026)Evidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion
Boswellia Knee Pain Randomized Trial1 2 3 4 6 7 8 9 10 1 Osteoarthritis (OA) is the most prevalent degenerative joint disease globally and the second most common rheumatologic condition [].4Muacevic Alexander (2026)Evidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion
topicBoswellia Knee Pain Randomized Trial
claimNutritional supplements are increasingly used for KOA due to their low risk, but direct comparative evidence on their efficacy and safety remains scarce.
evidence level1
citationZhang Y (2025)
sourceComparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis.
topicBoswellia Knee Pain Randomized Trial
claimBackground : Knee osteoarthritis (KOA) is a prevalent degenerative joint disease that can greatly affect quality of life in middle-aged and elderly individuals.
evidence level1
citationZhang Y (2025)
sourceComparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis.
topicBoswellia Knee Pain Randomized Trial
claimIt causes chronic pain, reduced mobility, and disability, affecting 607 million individuals worldwide, with nearly 46.6 million new cases annually [].
evidence level4
citationMuacevic Alexander (2026)
sourceEvidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion
topicBoswellia Knee Pain Randomized Trial
claim11 12 13 14 15 11 15 HLA-DRB1 HLA-DQB1 Genetic polymorphisms in sterol regulatory element-binding protein 2 (rs2228314) [], interleukin-6 (rs1800795) [], and resistin (RETN) [] in Indian and Pakistani cohorts and growth differentiation factor 5 (rs143383) [],, andin Thai populations [] are linked to OA risk.
evidence level4
citationMuacevic Alexander (2026)
sourceEvidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion
topicBoswellia Knee Pain Randomized Trial
claimNeed for expert opinion Despite growing clinical and mechanistic evidence for collagen supplementation in OA, several gaps and challenges remain in translating this knowledge into clinical practice, especially in the Indian subcontinent and Southeast Asia.
evidence level4
citationMuacevic Alexander (2026)
sourceEvidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion
topicBoswellia Knee Pain Randomized Trial
claim1 2 3 4 6 7 8 9 10 1 Osteoarthritis (OA) is the most prevalent degenerative joint disease globally and the second most common rheumatologic condition [].
evidence level4
citationMuacevic Alexander (2026)
sourceEvidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion

Source documents

  1. Comparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis.
  2. Evidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion