topicBoron Bone Health Randomized Trial
claimBoron neutron capture therapy (BNCT) is a biologically targeted, high-linear energy transfer radiotherapy that selectively delivers cytotoxic α-particles to boron-loaded tumor cells and has re-emerged with the development of hospital-compatible accelerator neutron sources and improved boron carriers.
evidence level4
citationKutuk T (2026)
sourceBoron Neutron Capture Therapy for High-Grade CNS Tumors: Mechanisms, Carriers, and Clinical Progress: A Narrative Review.
topicBoron Bone Health Randomized Trial
claimWe performed a structured literature review of PubMed, Embase, and the Cochrane Library through October 2025 to summarize the radiobiological rationale, boron delivery strategies, and clinical outcomes of BNCT in glioblastoma (GBM) and other high-grade central nervous system tumors.
evidence level4
citationKutuk T (2026)
sourceBoron Neutron Capture Therapy for High-Grade CNS Tumors: Mechanisms, Carriers, and Clinical Progress: A Narrative Review.
topicBoron Bone Health Randomized Trial
claimWe previously reported that, in a randomized, double-blind clinical trial with 180 healthy infants, an A2 β-casein IF containing high sn-2 palmitate levels, and casein phosphopeptides (CPP) improved stool consistency, gastrointestinal comfort, crying time, and bone mineral density.
evidence level4
citationWang L (2026)
sourceA2 β-casein infant formula with high sn-2 palmitate and casein phosphopeptides (CPP) supports energy and mineral absorption in Chinese infants.
topicBoron Bone Health Randomized Trial
claimRelative to standard cow's milk IF, the A2 β-casein, high sn-2 palmitate and CPP IF reduced fatty acid and calcium excretion, reduced calcium fatty acid soap formation, increased hair iron and zinc content, and was associated with lower cortisol levels.
evidence level4
citationWang L (2026)
sourceA2 β-casein infant formula with high sn-2 palmitate and casein phosphopeptides (CPP) supports energy and mineral absorption in Chinese infants.
topicBoron Bone Health Randomized Trial
claimInfant formula (IF) is essential when breastfeeding is not possible or sufficient.
evidence level4
citationWang L (2026)
sourceA2 β-casein infant formula with high sn-2 palmitate and casein phosphopeptides (CPP) supports energy and mineral absorption in Chinese infants.