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Blackcurrant Cognitive Performance Randomized Trial Evidence Table

Structured evidence table for Blackcurrant Cognitive Performance Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Blackcurrant Cognitive Performance Randomized TrialFour-week supplementation with a blackcurrant formulation enhances cognitive performance, reduces mental fatigue and modulates peripheral monoamine metabolism in older adults: a randomized, double-blind, placebo-controlled, crossover study2Lomiwes D (2026)Four-week supplementation with a blackcurrant formulation enhances cognitive performance, reduces mental fatigue and modulates peripheral monoamine metabolism in older adults: a randomized, double-blind, placebo-controlled, crossover study
Blackcurrant Cognitive Performance Randomized TrialThis bidirectional relationship is highlighted in preclinical research, where specific gut microbiota communities were associated with the bioavailability and memory-enhancing effects of grape-derived polyphenol supplementation in a sleep-induced model of cognitive impairment, whereas clinical efficacy was attenuated by antibiotic-induced dysbiosis [].2Gillies Nicola A (2024)Effects of a Flavonoid-Rich Blackcurrant Beverage on Markers of the Gut-Brain Axis in Healthy Females: Secondary Findings From a 4-Week Randomized Crossover Control Trial
Blackcurrant Cognitive Performance Randomized TrialWe also aimed to understand whether gut microbiome composition at baseline influenced cognitive or mood responses to the intervention or whether any changes in gut microbiome composition from baseline were associated with changes in behavioral parameters.2Gillies Nicola A (2024)Effects of a Flavonoid-Rich Blackcurrant Beverage on Markers of the Gut-Brain Axis in Healthy Females: Secondary Findings From a 4-Week Randomized Crossover Control Trial
Blackcurrant Cognitive Performance Randomized TrialFigure 2 31 32 FIGURE 2 The MTF (Purple Research Solutions) was used for 2 purposes in this trial: acting as a cognitive stressor to allow for stress reactivity measurements and assessment of cognitive function under increased cognitive demand.2Gillies Nicola A (2024)Effects of a Flavonoid-Rich Blackcurrant Beverage on Markers of the Gut-Brain Axis in Healthy Females: Secondary Findings From a 4-Week Randomized Crossover Control Trial
Blackcurrant Cognitive Performance Randomized Trial[1] [2] [3] 4 The microbiota–gut–brain axis is a potential target to curb the growing social and economic burden of mental health and neurologic disorders [,,].2Gillies Nicola A (2024)Effects of a Flavonoid-Rich Blackcurrant Beverage on Markers of the Gut-Brain Axis in Healthy Females: Secondary Findings From a 4-Week Randomized Crossover Control Trial
topicBlackcurrant Cognitive Performance Randomized Trial
claimFour-week supplementation with a blackcurrant formulation enhances cognitive performance, reduces mental fatigue and modulates peripheral monoamine metabolism in older adults: a randomized, double-blind, placebo-controlled, crossover study
evidence level2
citationLomiwes D (2026)
sourceFour-week supplementation with a blackcurrant formulation enhances cognitive performance, reduces mental fatigue and modulates peripheral monoamine metabolism in older adults: a randomized, double-blind, placebo-controlled, crossover study
topicBlackcurrant Cognitive Performance Randomized Trial
claimThis bidirectional relationship is highlighted in preclinical research, where specific gut microbiota communities were associated with the bioavailability and memory-enhancing effects of grape-derived polyphenol supplementation in a sleep-induced model of cognitive impairment, whereas clinical efficacy was attenuated by antibiotic-induced dysbiosis [].
evidence level2
citationGillies Nicola A (2024)
sourceEffects of a Flavonoid-Rich Blackcurrant Beverage on Markers of the Gut-Brain Axis in Healthy Females: Secondary Findings From a 4-Week Randomized Crossover Control Trial
topicBlackcurrant Cognitive Performance Randomized Trial
claimWe also aimed to understand whether gut microbiome composition at baseline influenced cognitive or mood responses to the intervention or whether any changes in gut microbiome composition from baseline were associated with changes in behavioral parameters.
evidence level2
citationGillies Nicola A (2024)
sourceEffects of a Flavonoid-Rich Blackcurrant Beverage on Markers of the Gut-Brain Axis in Healthy Females: Secondary Findings From a 4-Week Randomized Crossover Control Trial
topicBlackcurrant Cognitive Performance Randomized Trial
claimFigure 2 31 32 FIGURE 2 The MTF (Purple Research Solutions) was used for 2 purposes in this trial: acting as a cognitive stressor to allow for stress reactivity measurements and assessment of cognitive function under increased cognitive demand.
evidence level2
citationGillies Nicola A (2024)
sourceEffects of a Flavonoid-Rich Blackcurrant Beverage on Markers of the Gut-Brain Axis in Healthy Females: Secondary Findings From a 4-Week Randomized Crossover Control Trial
topicBlackcurrant Cognitive Performance Randomized Trial
claim[1] [2] [3] 4 The microbiota–gut–brain axis is a potential target to curb the growing social and economic burden of mental health and neurologic disorders [,,].
evidence level2
citationGillies Nicola A (2024)
sourceEffects of a Flavonoid-Rich Blackcurrant Beverage on Markers of the Gut-Brain Axis in Healthy Females: Secondary Findings From a 4-Week Randomized Crossover Control Trial

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Source documents

  1. Four-week supplementation with a blackcurrant formulation enhances cognitive performance, reduces mental fatigue and modulates peripheral monoamine metabolism in older adults: a randomized, double-blind, placebo-controlled, crossover study
  2. Effects of a Flavonoid-Rich Blackcurrant Beverage on Markers of the Gut-Brain Axis in Healthy Females: Secondary Findings From a 4-Week Randomized Crossover Control Trial