Structured evidence table for Black Seed Oil Skin Elasticity Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Black Seed Oil Skin Elasticity Randomized Trial | New evidence shows it amplifies oxidative stress via epigenetics in senescent cells []. | 3 | Zhu Liangyu (2026) | Plant-Derived Bioactive Compounds: Antioxidation, Autophagy, and Translational Applications in Skin Protection |
| Black Seed Oil Skin Elasticity Randomized Trial | This forms a “antioxidation→anti-inflammation→reduced ROS” virtuous cycle []. | 3 | Zhu Liangyu (2026) | Plant-Derived Bioactive Compounds: Antioxidation, Autophagy, and Translational Applications in Skin Protection |
| Black Seed Oil Skin Elasticity Randomized Trial | It reduces senescence-associated β-galactosidase (SA-β-gal)-positive cells. | 3 | Zhu Liangyu (2026) | Plant-Derived Bioactive Compounds: Antioxidation, Autophagy, and Translational Applications in Skin Protection |
| Black Seed Oil Skin Elasticity Randomized Trial | 1 2 3 Figure 1 4 5 6 7 8 9 10 10 The skin, as the body’s largest barrier organ, is constantly exposed to external aggressors such as ultraviolet radiation and environmental pollution, as well as intrinsic metabolic stress [,,]. | 3 | Zhu Liangyu (2026) | Plant-Derived Bioactive Compounds: Antioxidation, Autophagy, and Translational Applications in Skin Protection |
| Black Seed Oil Skin Elasticity Randomized Trial | An extract of Porphyridium cultivated in natural sunlight, rich in EPS and polydeoxyribonucleotides (PDRNs), significantly activated the ADORA2A receptor in a CHO model, as well as reduced inflammation and increased collagen and HA production, autophagic flux, and key autophagy gene expression in dermal fibroblast cultures. | 4 | Havas F (2026) | Hyaluronic Acid-like Skin Plumping and Radiance Benefits of a <i>Porphyridium</i> Sulfated Exopolysaccharide- and Natural PDRN-Rich Extract. |
| Black Seed Oil Skin Elasticity Randomized Trial | In a double-blind clinical trial with placebo and HA benchmark controls, the Porphyridium extract delivered significant HA-like skin plumpness, hydration, and radiance benefits, and reduced signs of aging. | 4 | Havas F (2026) | Hyaluronic Acid-like Skin Plumping and Radiance Benefits of a <i>Porphyridium</i> Sulfated Exopolysaccharide- and Natural PDRN-Rich Extract. |
| Black Seed Oil Skin Elasticity Randomized Trial | Red microalga Porphyridium cruentum produces a sulfated exopolysaccharide (EPS), which enables its survival in challenging intertidal and spray zones. | 4 | Havas F (2026) | Hyaluronic Acid-like Skin Plumping and Radiance Benefits of a <i>Porphyridium</i> Sulfated Exopolysaccharide- and Natural PDRN-Rich Extract. |
| Black Seed Oil Skin Elasticity Randomized Trial | Extracellular polysaccharide hyaluronic acid (HA) plays important roles in skin hydration, elasticity, and volume. | 4 | Havas F (2026) | Hyaluronic Acid-like Skin Plumping and Radiance Benefits of a <i>Porphyridium</i> Sulfated Exopolysaccharide- and Natural PDRN-Rich Extract. |
Source documents