Black Seed Oil Cardiometabolic Meta-Analysis Evidence Table

Structured evidence table for Black Seed Oil Cardiometabolic Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Black Seed Oil Cardiometabolic Meta-AnalysisIn addition to the chronic effects associated with regular pulse consumption, acute modulation of the postprandial response to pulse-enriched meals is of great interest.1Schiemann Tim B (2026)Acute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies
Black Seed Oil Cardiometabolic Meta-AnalysisPostprandial oxidative stress is associated with postprandial low-grade inflammation and endothelial activation.The accumulation of postprandial metabolic processes alongside a hyperenergetic diet appears to be associated with an increased long-term risk of the development of cardiometabolic and neurodegenerative diseases,with postprandial lipidemia,glycemia,and inflammationrepresenting independent risk factors.1Schiemann Tim B (2026)Acute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies
Black Seed Oil Cardiometabolic Meta-AnalysisThe overall quality of each study was determined to be good if the study scored low risk for all domains, fair if the study scored some concerns for one or more domain, and poor if the study scored high risk for one or more domain.1Schiemann Tim B (2026)Acute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies
Black Seed Oil Cardiometabolic Meta-AnalysisFabaceae Table 1 Legumes belong to thefamily and can be split into two subcategories: oil-seed legumes and non-oil-seed legumes.1Schiemann Tim B (2026)Acute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies
Black Seed Oil Cardiometabolic Meta-AnalysisMechanistically, these conditions are characterized by low-grade chronic inflammation, increased production of pro-inflammatory cytokines and oxidative stress, hyperinsulinemia, insulin resistance, dyslipidemia, endothelial dysfunction, and gut dysbiosis—all of which may contribute to disease progression and metabolic complications [].3Gaddam Indraja (2026)Effects of Grape and Grape-Derived Bioactives on Inflammation and Immune-Driven Mechanisms Within the Context of Cardiometabolic Health and Aging: A Review
Black Seed Oil Cardiometabolic Meta-AnalysisEarlier onset of metabolic dysfunction is associated with greater risk of age-related physical decline and comorbidities [], which is a critical clinical and public health concern given that the population in the U.S.3Gaddam Indraja (2026)Effects of Grape and Grape-Derived Bioactives on Inflammation and Immune-Driven Mechanisms Within the Context of Cardiometabolic Health and Aging: A Review
Black Seed Oil Cardiometabolic Meta-AnalysisEvidence from mechanistic and clinical studies demonstrates that bioactive-rich foods and their functional components can modulate disease-mediating immune and inflammatory pathways [].3Gaddam Indraja (2026)Effects of Grape and Grape-Derived Bioactives on Inflammation and Immune-Driven Mechanisms Within the Context of Cardiometabolic Health and Aging: A Review
Black Seed Oil Cardiometabolic Meta-AnalysisThere has been a steady increase in the prevalence of chronic conditions over the past 20 years that is expected to continue, which represents major and growing public health concerns worldwide [].3Gaddam Indraja (2026)Effects of Grape and Grape-Derived Bioactives on Inflammation and Immune-Driven Mechanisms Within the Context of Cardiometabolic Health and Aging: A Review
topicBlack Seed Oil Cardiometabolic Meta-Analysis
claimIn addition to the chronic effects associated with regular pulse consumption, acute modulation of the postprandial response to pulse-enriched meals is of great interest.
evidence level1
citationSchiemann Tim B (2026)
sourceAcute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies
topicBlack Seed Oil Cardiometabolic Meta-Analysis
claimPostprandial oxidative stress is associated with postprandial low-grade inflammation and endothelial activation.The accumulation of postprandial metabolic processes alongside a hyperenergetic diet appears to be associated with an increased long-term risk of the development of cardiometabolic and neurodegenerative diseases,with postprandial lipidemia,glycemia,and inflammationrepresenting independent risk factors.
evidence level1
citationSchiemann Tim B (2026)
sourceAcute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies
topicBlack Seed Oil Cardiometabolic Meta-Analysis
claimThe overall quality of each study was determined to be good if the study scored low risk for all domains, fair if the study scored some concerns for one or more domain, and poor if the study scored high risk for one or more domain.
evidence level1
citationSchiemann Tim B (2026)
sourceAcute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies
topicBlack Seed Oil Cardiometabolic Meta-Analysis
claimFabaceae Table 1 Legumes belong to thefamily and can be split into two subcategories: oil-seed legumes and non-oil-seed legumes.
evidence level1
citationSchiemann Tim B (2026)
sourceAcute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies
topicBlack Seed Oil Cardiometabolic Meta-Analysis
claimMechanistically, these conditions are characterized by low-grade chronic inflammation, increased production of pro-inflammatory cytokines and oxidative stress, hyperinsulinemia, insulin resistance, dyslipidemia, endothelial dysfunction, and gut dysbiosis—all of which may contribute to disease progression and metabolic complications [].
evidence level3
citationGaddam Indraja (2026)
sourceEffects of Grape and Grape-Derived Bioactives on Inflammation and Immune-Driven Mechanisms Within the Context of Cardiometabolic Health and Aging: A Review
topicBlack Seed Oil Cardiometabolic Meta-Analysis
claimEarlier onset of metabolic dysfunction is associated with greater risk of age-related physical decline and comorbidities [], which is a critical clinical and public health concern given that the population in the U.S.
evidence level3
citationGaddam Indraja (2026)
sourceEffects of Grape and Grape-Derived Bioactives on Inflammation and Immune-Driven Mechanisms Within the Context of Cardiometabolic Health and Aging: A Review
topicBlack Seed Oil Cardiometabolic Meta-Analysis
claimEvidence from mechanistic and clinical studies demonstrates that bioactive-rich foods and their functional components can modulate disease-mediating immune and inflammatory pathways [].
evidence level3
citationGaddam Indraja (2026)
sourceEffects of Grape and Grape-Derived Bioactives on Inflammation and Immune-Driven Mechanisms Within the Context of Cardiometabolic Health and Aging: A Review
topicBlack Seed Oil Cardiometabolic Meta-Analysis
claimThere has been a steady increase in the prevalence of chronic conditions over the past 20 years that is expected to continue, which represents major and growing public health concerns worldwide [].
evidence level3
citationGaddam Indraja (2026)
sourceEffects of Grape and Grape-Derived Bioactives on Inflammation and Immune-Driven Mechanisms Within the Context of Cardiometabolic Health and Aging: A Review

Source documents

  1. Acute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies
  2. Effects of Grape and Grape-Derived Bioactives on Inflammation and Immune-Driven Mechanisms Within the Context of Cardiometabolic Health and Aging: A Review