topicBlack Seed Oil Allergic Rhinitis Meta-Analysis
claimAlthough alfalfa seeds have demonstrated anti-inflammatory and antihistamine effects (;), evidence supporting the routine use of black cumin supplements for treating allergic rhinitis is lacking.
evidence level1
citationHe Yuxiao (2024)
sourceMeta-analysis of randomized controlled trials assessing the efficacy of nigella sativa supplementation for allergic rhinitis treatment
topicBlack Seed Oil Allergic Rhinitis Meta-Analysis
claimNo outcome data were missing, no selective reporting was found, and other sources of bias were unknown ().
evidence level1
citationHe Yuxiao (2024)
sourceMeta-analysis of randomized controlled trials assessing the efficacy of nigella sativa supplementation for allergic rhinitis treatment
topicBlack Seed Oil Allergic Rhinitis Meta-Analysis
claimAccording to our analysis, relative to control group, observation group exhibited the markedly increased total effective rate for allergic rhinitis [OR = 4.24, 95% CI [2.57,7.27],< 0.00001](), which indicated that the treatment effect on allergic rhinitis patients in the experimental group was significantly better than that in the control group.
evidence level1
citationHe Yuxiao (2024)
sourceMeta-analysis of randomized controlled trials assessing the efficacy of nigella sativa supplementation for allergic rhinitis treatment
topicBlack Seed Oil Allergic Rhinitis Meta-Analysis
claimZhang and Zhang, 2014 Otolaryngology, 2022 Nigella sativa, commonly known as black cumin, is an annual plant that belongs to the genus Nigella of the Ranunculaceae family.
evidence level1
citationHe Yuxiao (2024)
sourceMeta-analysis of randomized controlled trials assessing the efficacy of nigella sativa supplementation for allergic rhinitis treatment
topicBlack Seed Oil Allergic Rhinitis Meta-Analysis
claimIn particular, it may be effective in the management of conditions such as hypertension, diabetes, and liver disease, alongside other potential health benefits, such as its ability to support gastrointestinal health, cardiovascular risk reduction, and metabolic control.
evidence level4
citationSanlier Nevin (2026)
sourceFrom Husks and Seeds to Health: an Inevitable Outcome Rather than a Fluke
topicBlack Seed Oil Allergic Rhinitis Meta-Analysis
claimStudies also emphasize its various metabolic and hepatoprotective effects, including the modulation of bile acid metabolism and the activation of pathways associated with the farnesoid X receptor.
evidence level4
citationSanlier Nevin (2026)
sourceFrom Husks and Seeds to Health: an Inevitable Outcome Rather than a Fluke
topicBlack Seed Oil Allergic Rhinitis Meta-Analysis
claimIn an animal study conducted with rats, psyllium was found to have antioxidant and anti-inflammatory effects [].
evidence level4
citationSanlier Nevin (2026)
sourceFrom Husks and Seeds to Health: an Inevitable Outcome Rather than a Fluke
topicBlack Seed Oil Allergic Rhinitis Meta-Analysis
claimPlantago ovata 1 2 3 4 5 The shells or husks ofseeds, also known as psyllium, ispaghula, or isabgol, are attracting attention in recent years due to their health benefits [,].
evidence level4
citationSanlier Nevin (2026)
sourceFrom Husks and Seeds to Health: an Inevitable Outcome Rather than a Fluke