topicBlack Seed Cardiometabolic Markers Meta-Analysis
claimAdditionally, 3 of 5 studies found a significantly reduced feeling of hunger following meals enriched with pulses compared with the control meal, while the remaining 2 studies found a nonsignificant reduction.
evidence level1
citationSchiemann TB (2026)
sourceAcute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies.
topicBlack Seed Cardiometabolic Markers Meta-Analysis
claimAlthough the studies examining satiety and fullness found increased satiation following pulse-enriched meals, only 1 of 6 studies found a significantly greater increase in satiety compared with the control, and 3 of 6 studies found a significantly greater increase in fullness.
evidence level1
citationSchiemann TB (2026)
sourceAcute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies.
topicBlack Seed Cardiometabolic Markers Meta-Analysis
claimConclusion This systematic review confirmed that non-oil-seed pulses can attenuate postprandial glycemia and lipemia and can therefore be classified as low-glycemic food.
evidence level1
citationSchiemann TB (2026)
sourceAcute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies.
topicBlack Seed Cardiometabolic Markers Meta-Analysis
claimBackground Non-oil-seed pulses offer a plant-based source of dietary protein and further nutritionally valuable nutrients such as essential micronutrients and dietary fiber, making them a key component of sustainable diets emphasizing plant protein.
evidence level1
citationSchiemann TB (2026)
sourceAcute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies.
topicBlack Seed Cardiometabolic Markers Meta-Analysis
claimChronic low-grade and immune-mediated inflammation underlies the pathophysiology of metabolic and systemic tissue dysfunction associated with cardiometabolic disease development and accelerated aging, whereas therapeutic and preventative strategies to reduce inflammation and promote immune function yield beneficial health outcomes.
evidence level3
citationGaddam I (2026)
sourceEffects of Grape and Grape-Derived Bioactives on Inflammation and Immune-Driven Mechanisms Within the Context of Cardiometabolic Health and Aging: A Review.
topicBlack Seed Cardiometabolic Markers Meta-Analysis
claimEvidence from cell and animal studies demonstrates that consumption of grapes, grape-based extracts and preparations, and grape-derived bioactive compounds exert beneficial anti-inflammatory and immunomodulatory effects, which are associated with improvements in metabolic profiles.
evidence level3
citationGaddam I (2026)
sourceEffects of Grape and Grape-Derived Bioactives on Inflammation and Immune-Driven Mechanisms Within the Context of Cardiometabolic Health and Aging: A Review.
topicBlack Seed Cardiometabolic Markers Meta-Analysis
claimHowever, results from human intervention trials investigating grape effects on inflammatory and immune markers are more limited and report varied effects on improvements in clinical and experimental biomarkers indicative of cardiometabolic disease risk and healthy aging, such as serum lipids, blood pressure, insulin resistance, oxidative stress, gut dysbiosis, and cognitive function.
evidence level3
citationGaddam I (2026)
sourceEffects of Grape and Grape-Derived Bioactives on Inflammation and Immune-Driven Mechanisms Within the Context of Cardiometabolic Health and Aging: A Review.
topicBlack Seed Cardiometabolic Markers Meta-Analysis
claimCardiometabolic disease and age-related health complications are significant clinical and public health concerns that impact an individual's overall quality of life and longevity.
evidence level3
citationGaddam I (2026)
sourceEffects of Grape and Grape-Derived Bioactives on Inflammation and Immune-Driven Mechanisms Within the Context of Cardiometabolic Health and Aging: A Review.