evidence table
Black Seed Blood Pressure Randomized Trial Evidence Table
Structured evidence table for Black Seed Blood Pressure Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Black Seed Blood Pressure Randomized Trial | Severity, frequency and duration of migraine attacks, headache daily result (HDR), quality of life, migraine disability, mental health, anthropometric indices, blood pressure, and serum levels of calcitonin gene-related peptide (CGRP), vascular cell adhesion molecules-1, total antioxidant capacity, and malondialdehyde were measured at baseline and end of the trial. | 2 | Eshaghian N (2025) | Effects of grape seed extract supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in patients with migraine: A double-blinded randomized placebo-controlled clinical trial. |
| Black Seed Blood Pressure Randomized Trial | Conclusion This study provides evidence supporting the beneficial effects of GSE supplement on the serum levels of CGRP. | 2 | Eshaghian N (2025) | Effects of grape seed extract supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in patients with migraine: A double-blinded randomized placebo-controlled clinical trial. |
| Black Seed Blood Pressure Randomized Trial | Background The current study was conducted to assess the effect of grape seed extract (GSE) supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in migraine patients. | 2 | Eshaghian N (2025) | Effects of grape seed extract supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in patients with migraine: A double-blinded randomized placebo-controlled clinical trial. |
| Black Seed Blood Pressure Randomized Trial | Materials and methods In this randomized double-blinded controlled clinical trial, 50 patients with migraine were randomly allocated to receive either 200 mg/day GSE supplement ( n = 25) or placebo ( n = 25) for 8 weeks. | 2 | Eshaghian N (2025) | Effects of grape seed extract supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in patients with migraine: A double-blinded randomized placebo-controlled clinical trial. |
| Black Seed Blood Pressure Randomized Trial | Some of these phytochemicals are unique to specific H/S, for example, piperine is exclusively found in black pepper, while cinnamaldehyde and coumarin are only found in cinnamon. | 3 | Huang Yudai (2026) | Phytochemicals From Herbs and Spices: Their Absorption, Metabolism, and Relationship to Clinical Outcomes |
| Black Seed Blood Pressure Randomized Trial | Alternatively, other phytochemicals are found in different amounts in a variety of H/S, such as hydroxycinnamic acids and hydroxybenzoic acids, presenting in both the Italian herb mixture and cinnamon. | 3 | Huang Yudai (2026) | Phytochemicals From Herbs and Spices: Their Absorption, Metabolism, and Relationship to Clinical Outcomes |
| Black Seed Blood Pressure Randomized Trial | Terpenoids were only found in the Italian herb mixture, with a concentration of 498.6 ± 29.9 mg per 100 g. | 3 | Huang Yudai (2026) | Phytochemicals From Herbs and Spices: Their Absorption, Metabolism, and Relationship to Clinical Outcomes |
| Black Seed Blood Pressure Randomized Trial | Herbs and spices (H/S) have been utilized as folk medicine in different parts of the world for centuries and have significance in cultural, religious and traditional healing practices. | 3 | Huang Yudai (2026) | Phytochemicals From Herbs and Spices: Their Absorption, Metabolism, and Relationship to Clinical Outcomes |
Source documents
- Effects of grape seed extract supplementation on inflammatory biomarkers, oxidative stress, clinical symptoms, and quality of life in patients with migraine: A double-blinded randomized placebo-controlled clinical trial.
- Phytochemicals From Herbs and Spices: Their Absorption, Metabolism, and Relationship to Clinical Outcomes