Black Garlic Cholesterol Randomized Trial Evidence Table

Structured evidence table for Black Garlic Cholesterol Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Black Garlic Cholesterol Randomized TrialBackground Aged black garlic (ABG) is rich in organosulfur compounds such as S-allyl-cysteine (SAC) and may influence lipid metabolism, although evidence from controlled trials remains limited.2Serrano JCE (2026)Effects of aged black garlic (ABG10+<sup>®</sup>) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.
Black Garlic Cholesterol Randomized TrialIn secondary exploratory analyses of NMR-derived lipoprotein subclasses, nominally significant differences were observed: ABG was associated with a reduction in the total number of particles and HDL particles.2Serrano JCE (2026)Effects of aged black garlic (ABG10+<sup>®</sup>) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.
Black Garlic Cholesterol Randomized TrialConclusion Low-dose ABG supplementation did not significantly modify conventional lipid markers in Grade I hypertensive individuals.2Serrano JCE (2026)Effects of aged black garlic (ABG10+<sup>®</sup>) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.
Black Garlic Cholesterol Randomized TrialThe aim of this study was to evaluate the impact of a low-dose SAC-optimized ABG on blood lipid profiles in Grade I hypertensive individuals.2Serrano JCE (2026)Effects of aged black garlic (ABG10+<sup>®</sup>) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.
Black Garlic Cholesterol Randomized Trial1 2 3 4 5 6 6 Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease, refers to excessive accumulation of fat in the liver, accompanied by at least one cardiometabolic risk factor (i.e., overweight/obesity, abnormal glucose metabolism, elevated blood pressure, elevated triglycerides, and reduced high-density lipoprotein cholesterol) [].3Sun Niuniu (2026)Protective Effects of Allicin and Garlic-Derived Interventions Against Metabolic Dysfunction-Associated Steatotic Liver Disease: Current Evidence and Mechanistic Insights
Black Garlic Cholesterol Randomized TrialMASLD ranges from simple steatosis to metabolic dysfunction-associated steatohepatitis, with potential progression to cirrhosis and hepatocellular carcinoma [].3Sun Niuniu (2026)Protective Effects of Allicin and Garlic-Derived Interventions Against Metabolic Dysfunction-Associated Steatotic Liver Disease: Current Evidence and Mechanistic Insights
Black Garlic Cholesterol Randomized TrialAffecting approximately 30–40% of the global adult population [], MASLD is associated with an increased risk of cardiovascular disease, chronic kidney disease, and malignant tumors of the liver and extrahepatic sites [].3Sun Niuniu (2026)Protective Effects of Allicin and Garlic-Derived Interventions Against Metabolic Dysfunction-Associated Steatotic Liver Disease: Current Evidence and Mechanistic Insights
topicBlack Garlic Cholesterol Randomized Trial
claimBackground Aged black garlic (ABG) is rich in organosulfur compounds such as S-allyl-cysteine (SAC) and may influence lipid metabolism, although evidence from controlled trials remains limited.
evidence level2
citationSerrano JCE (2026)
sourceEffects of aged black garlic (ABG10+<sup>®</sup>) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.
topicBlack Garlic Cholesterol Randomized Trial
claimIn secondary exploratory analyses of NMR-derived lipoprotein subclasses, nominally significant differences were observed: ABG was associated with a reduction in the total number of particles and HDL particles.
evidence level2
citationSerrano JCE (2026)
sourceEffects of aged black garlic (ABG10+<sup>®</sup>) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.
topicBlack Garlic Cholesterol Randomized Trial
claimConclusion Low-dose ABG supplementation did not significantly modify conventional lipid markers in Grade I hypertensive individuals.
evidence level2
citationSerrano JCE (2026)
sourceEffects of aged black garlic (ABG10+<sup>®</sup>) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.
topicBlack Garlic Cholesterol Randomized Trial
claimThe aim of this study was to evaluate the impact of a low-dose SAC-optimized ABG on blood lipid profiles in Grade I hypertensive individuals.
evidence level2
citationSerrano JCE (2026)
sourceEffects of aged black garlic (ABG10+<sup>®</sup>) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.
topicBlack Garlic Cholesterol Randomized Trial
claim1 2 3 4 5 6 6 Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease, refers to excessive accumulation of fat in the liver, accompanied by at least one cardiometabolic risk factor (i.e., overweight/obesity, abnormal glucose metabolism, elevated blood pressure, elevated triglycerides, and reduced high-density lipoprotein cholesterol) [].
evidence level3
citationSun Niuniu (2026)
sourceProtective Effects of Allicin and Garlic-Derived Interventions Against Metabolic Dysfunction-Associated Steatotic Liver Disease: Current Evidence and Mechanistic Insights
topicBlack Garlic Cholesterol Randomized Trial
claimMASLD ranges from simple steatosis to metabolic dysfunction-associated steatohepatitis, with potential progression to cirrhosis and hepatocellular carcinoma [].
evidence level3
citationSun Niuniu (2026)
sourceProtective Effects of Allicin and Garlic-Derived Interventions Against Metabolic Dysfunction-Associated Steatotic Liver Disease: Current Evidence and Mechanistic Insights
topicBlack Garlic Cholesterol Randomized Trial
claimAffecting approximately 30–40% of the global adult population [], MASLD is associated with an increased risk of cardiovascular disease, chronic kidney disease, and malignant tumors of the liver and extrahepatic sites [].
evidence level3
citationSun Niuniu (2026)
sourceProtective Effects of Allicin and Garlic-Derived Interventions Against Metabolic Dysfunction-Associated Steatotic Liver Disease: Current Evidence and Mechanistic Insights

Source documents

  1. Effects of aged black garlic (ABG10+<sup>®</sup>) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.
  2. Protective Effects of Allicin and Garlic-Derived Interventions Against Metabolic Dysfunction-Associated Steatotic Liver Disease: Current Evidence and Mechanistic Insights