topicBifidobacterium Longum Sleep Randomized Trial
claimTwenty RCTs were included, of which 15 were assessed as having a low risk of bias and five as having a high risk of bias.
evidence level1
citationDas M (2026)
sourceFrom Gut to Mind: Impact of Probiotics on Depression, Anxiety, Mood, Gut Microbiota, Sleep and Stress-A Systematic Review of RCTs.
topicBifidobacterium Longum Sleep Randomized Trial
claimOverall, probiotics were associated with improvements in depression, anxiety, sleep quality, mood, cognition, quality of life, and beneficial gut microbial populations, although findings for cortisol and stress-related outcomes were inconsistent.
evidence level1
citationDas M (2026)
sourceFrom Gut to Mind: Impact of Probiotics on Depression, Anxiety, Mood, Gut Microbiota, Sleep and Stress-A Systematic Review of RCTs.
topicBifidobacterium Longum Sleep Randomized Trial
claimBackground Probiotic supplementation may influence mental health through the gut-brain axis, with potential effects on depression, anxiety, sleep, cognition, stress hormones, and gut microbial composition.
evidence level1
citationDas M (2026)
sourceFrom Gut to Mind: Impact of Probiotics on Depression, Anxiety, Mood, Gut Microbiota, Sleep and Stress-A Systematic Review of RCTs.
topicBifidobacterium Longum Sleep Randomized Trial
claimThis systematic review aimed to evaluate the effects of probiotics on psychological, physiological, and gut microbiome-related outcomes across diverse populations.
evidence level1
citationDas M (2026)
sourceFrom Gut to Mind: Impact of Probiotics on Depression, Anxiety, Mood, Gut Microbiota, Sleep and Stress-A Systematic Review of RCTs.
topicBifidobacterium Longum Sleep Randomized Trial
claimAmong the measured SCFAs, only the butyric acid concentration in PG increased significantly during supplementation (baseline vs.
evidence level2
citationDrzymała S (2026)
sourceThe Impact of Psychobiotic Therapy on Anxiety and Depressive Symptoms in Patients with Post-COVID Syndrome-A Randomized, Double-Blind, Placebo-Controlled Trial.
topicBifidobacterium Longum Sleep Randomized Trial
claimBackground : Recovering from COVID-19 does not always lead to complete recovery, and many patients report symptoms of anxiety and depression.
evidence level2
citationDrzymała S (2026)
sourceThe Impact of Psychobiotic Therapy on Anxiety and Depressive Symptoms in Patients with Post-COVID Syndrome-A Randomized, Double-Blind, Placebo-Controlled Trial.
topicBifidobacterium Longum Sleep Randomized Trial
claimThe aim of this study was to evaluate the impact of psychobiotic therapy on the effectiveness of treating anxiety and depressive symptoms in individuals who had previously experienced COVID-19.
evidence level2
citationDrzymała S (2026)
sourceThe Impact of Psychobiotic Therapy on Anxiety and Depressive Symptoms in Patients with Post-COVID Syndrome-A Randomized, Double-Blind, Placebo-Controlled Trial.