Structured evidence table for Betaine Supplementation Exercise Performance Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Betaine Supplementation Exercise Performance Randomized Trial | The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), and study quality was assessed using the Cochrane Risk of Bias Tool. | 1 | Perreras MSL (2025) | Effects of betaine supplementation on endurance exercise performance: a systematic review. |
| Betaine Supplementation Exercise Performance Randomized Trial | Of these, two studies demonstrated a significant interaction effect on maximum oxygen consumption and mean power at the latter stage of the Wingate Anaerobic Test, two reported a main effect of treatment on mean power, peak power, and oxygen consumption, and one found significant differences in oxygen consumption and blood lactate levels. | 1 | Perreras MSL (2025) | Effects of betaine supplementation on endurance exercise performance: a systematic review. |
| Betaine Supplementation Exercise Performance Randomized Trial | Conclusion These findings highlight the paucity of evidence regarding the ergogenic potential of betaine in endurance exercise performance and underscore the need for additional, more rigorous research to determine its effectiveness. | 1 | Perreras MSL (2025) | Effects of betaine supplementation on endurance exercise performance: a systematic review. |
| Betaine Supplementation Exercise Performance Randomized Trial | Purpose Betaine has been studied for its potential ergogenic effects on strength, power, and body composition. | 1 | Perreras MSL (2025) | Effects of betaine supplementation on endurance exercise performance: a systematic review. |
| Betaine Supplementation Exercise Performance Randomized Trial | Emerging empirical evidence indicates that a simultaneous approach targeting mitochondrial function, one-carbon metabolism, and catecholaminergic pathways may yield a more efficacious strategy than isolated interventions (). | 3 | Xu Chunhong (2026) | Skeletal muscle mitochondrial–methylation–neurotransmitter crosstalk: a novel synergistic model of betaine, tyrosine, and Cordyceps for exercise performance in older adults, individuals with metabolic disorders, and healthy populations |
| Betaine Supplementation Exercise Performance Randomized Trial | The dysregulation of methylation pathways has been associated with the onset of metabolic syndrome, cognitive decline, and muscular dysfunction (). | 3 | Xu Chunhong (2026) | Skeletal muscle mitochondrial–methylation–neurotransmitter crosstalk: a novel synergistic model of betaine, tyrosine, and Cordyceps for exercise performance in older adults, individuals with metabolic disorders, and healthy populations |
| Betaine Supplementation Exercise Performance Randomized Trial | The process of aging, along with metabolic disorders, is often correlated with compromised dopaminergic signaling, which contributes to diminished physical performance and increased levels of fatigue. | 3 | Xu Chunhong (2026) | Skeletal muscle mitochondrial–methylation–neurotransmitter crosstalk: a novel synergistic model of betaine, tyrosine, and Cordyceps for exercise performance in older adults, individuals with metabolic disorders, and healthy populations |
| Betaine Supplementation Exercise Performance Randomized Trial | 1 2 3 4 5 6 7 8 9 Athletic performance represents a multifaceted phenotype influenced by the interplay of mitochondrial bioenergetics, epigenetic modulation, and neurotransmitter signaling (). | 3 | Xu Chunhong (2026) | Skeletal muscle mitochondrial–methylation–neurotransmitter crosstalk: a novel synergistic model of betaine, tyrosine, and Cordyceps for exercise performance in older adults, individuals with metabolic disorders, and healthy populations |
Source documents