Structured evidence table for Betaine Fatigue Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Betaine Fatigue Randomized Trial | The dynamic nature of soccer, where tactical and physical demands uniquely interact in each match, requires a rigorous analysis of how various forms of fatigue interact and affect decision making, skill execution, and injury risk (). | 1 | Gnanasigamani Moses (2026) | Multifactorial Thresholds of Psychomotor Fatigue in Soccer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials |
| Betaine Fatigue Randomized Trial | Shortened off-seasons exacerbate this issue, leaving players with insufficient time to fully recover, which heightens the risk of cumulative fatigue and injuries. | 1 | Gnanasigamani Moses (2026) | Multifactorial Thresholds of Psychomotor Fatigue in Soccer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials |
| Betaine Fatigue Randomized Trial | High-Intensity Interval Training (HIIT) has been widely adopted to improve anaerobic capacity and the ability to perform repeated high-intensity efforts, reflecting the increased physical and cognitive demands of the sport (;;). | 1 | Gnanasigamani Moses (2026) | Multifactorial Thresholds of Psychomotor Fatigue in Soccer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials |
| Betaine Fatigue Randomized Trial | Clemente et al., 2022 Jastrzębski et al., 2025 During the past few decades, soccer has undergone significant transformations, marked by noticeable increases in game intensity, players’ performance demands, and overall pace (). | 1 | Gnanasigamani Moses (2026) | Multifactorial Thresholds of Psychomotor Fatigue in Soccer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials |
| Betaine Fatigue Randomized Trial | No trial differences were found for I-FABP (interaction effect, p = 0.076), L: 13 CM ( p = 0.559), the neutrophil/lymphocyte ratio ( p = 0.171), serum cortisol ( p = 0.982), serum myoglobin ( p = 0.942), or serum creatine kinase ( p = 0.694). | 4 | Nieman DC (2025) | Betaine Supplementation Improves 60 km Cycling Time Trial Performance and One-Carbon Metabolism in Cyclists During Recovery. |
| Betaine Fatigue Randomized Trial | Conclusions Betaine supplementation modestly improved 60 km cycling performance but had no effect on gut permeability. | 4 | Nieman DC (2025) | Betaine Supplementation Improves 60 km Cycling Time Trial Performance and One-Carbon Metabolism in Cyclists During Recovery. |
| Betaine Fatigue Randomized Trial | Background/objectives This study examined the effects of 2 weeks of betaine versus placebo supplementation (3 g/d) on 60 km cycling performance, gut permeability, and shifts in plasma metabolites. | 4 | Nieman DC (2025) | Betaine Supplementation Improves 60 km Cycling Time Trial Performance and One-Carbon Metabolism in Cyclists During Recovery. |
| Betaine Fatigue Randomized Trial | A randomized, placebo-controlled, double-blind, crossover design was used with two 2-week supplementation periods and a 2-week washout period. | 4 | Nieman DC (2025) | Betaine Supplementation Improves 60 km Cycling Time Trial Performance and One-Carbon Metabolism in Cyclists During Recovery. |
Source documents