Structured evidence table for Betaine Exercise Fatigue Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Betaine Exercise Fatigue Randomized Trial | Comprehensive descriptions of the mechanisms underlying central fatigue can be found in recent reviews (Zhou et al. ). | 4 | Yang Yaqin (2026) | Nutritional Interventions and Acupuncture‐Based Strategies for Exercise‐Induced Fatigue and Recovery: Mechanisms and Integrative Perspectives |
| Betaine Exercise Fatigue Randomized Trial | In addition, reduced oxidative phosphorylation capacity, loss of mitochondrial membrane potential, and accumulation of damaged mitochondria compromise ATP supply and exacerbate ROS generation (Powers et al. ; Yu et al. ). | 4 | Yang Yaqin (2026) | Nutritional Interventions and Acupuncture‐Based Strategies for Exercise‐Induced Fatigue and Recovery: Mechanisms and Integrative Perspectives |
| Betaine Exercise Fatigue Randomized Trial | In addition, NSAIDs are associated with an increased risk of adverse gastrointestinal, renal, and cardiovascular effects, and with interference with adaptive training responses (Bacchi et al. ). | 4 | Yang Yaqin (2026) | Nutritional Interventions and Acupuncture‐Based Strategies for Exercise‐Induced Fatigue and Recovery: Mechanisms and Integrative Perspectives |
| Betaine Exercise Fatigue Randomized Trial | 2025 2026 2023 2017 2023 Exercise‐induced fatigue (EIF) is a reversible decline in the ability to sustain a given exercise intensity or power output under a defined workload. | 4 | Yang Yaqin (2026) | Nutritional Interventions and Acupuncture‐Based Strategies for Exercise‐Induced Fatigue and Recovery: Mechanisms and Integrative Perspectives |
| Betaine Exercise Fatigue Randomized Trial | No trial differences were found for I-FABP (interaction effect, p = 0.076), L: 13 CM ( p = 0.559), the neutrophil/lymphocyte ratio ( p = 0.171), serum cortisol ( p = 0.982), serum myoglobin ( p = 0.942), or serum creatine kinase ( p = 0.694). | 4 | Nieman DC (2025) | Betaine Supplementation Improves 60 km Cycling Time Trial Performance and One-Carbon Metabolism in Cyclists During Recovery. |
| Betaine Exercise Fatigue Randomized Trial | Conclusions Betaine supplementation modestly improved 60 km cycling performance but had no effect on gut permeability. | 4 | Nieman DC (2025) | Betaine Supplementation Improves 60 km Cycling Time Trial Performance and One-Carbon Metabolism in Cyclists During Recovery. |
| Betaine Exercise Fatigue Randomized Trial | Background/objectives This study examined the effects of 2 weeks of betaine versus placebo supplementation (3 g/d) on 60 km cycling performance, gut permeability, and shifts in plasma metabolites. | 4 | Nieman DC (2025) | Betaine Supplementation Improves 60 km Cycling Time Trial Performance and One-Carbon Metabolism in Cyclists During Recovery. |
| Betaine Exercise Fatigue Randomized Trial | A randomized, placebo-controlled, double-blind, crossover design was used with two 2-week supplementation periods and a 2-week washout period. | 4 | Nieman DC (2025) | Betaine Supplementation Improves 60 km Cycling Time Trial Performance and One-Carbon Metabolism in Cyclists During Recovery. |
Source documents