topicBeta Glucan Immune Function Randomized Trial
claimHowever, clinical evidence linking their intake to site-specific upper respiratory mucosal immune health in humans remains limited.
evidence level2
citationKanno T (2026)
sourceDietary β-1,3/1,6-Glucan from Baker's Yeast Supports Upper Respiratory Mucosal Immune Health in Healthy Adults: Evidence from a Randomized, Double-Blind, Placebo-Controlled Trial.
topicBeta Glucan Immune Function Randomized Trial
claimSC-BG intake also attenuated declines in s-IgA levels in the posterior oropharyngeal wall and nasopharynx and increased salivary lysozyme concentrations.
evidence level2
citationKanno T (2026)
sourceDietary β-1,3/1,6-Glucan from Baker's Yeast Supports Upper Respiratory Mucosal Immune Health in Healthy Adults: Evidence from a Randomized, Double-Blind, Placebo-Controlled Trial.
topicBeta Glucan Immune Function Randomized Trial
claimBackground/Objective : Dietary polysaccharides are increasingly recognized as functional nutritional components that support human health through modulation of immune function.
evidence level2
citationKanno T (2026)
sourceDietary β-1,3/1,6-Glucan from Baker's Yeast Supports Upper Respiratory Mucosal Immune Health in Healthy Adults: Evidence from a Randomized, Double-Blind, Placebo-Controlled Trial.
topicBeta Glucan Immune Function Randomized Trial
claimPreclinical and emerging clinical evidence supports broad therapeutic potential across multiple disease domains, including inflammatory bowel disease, metabolic disorders, respiratory infections, and cancer.
evidence level4
citationSamiksha F (2026)
sourceFungal β-1,3-glucans: Cell Wall Constituents That Promote Gut Health Through Innate Immune Modulation.
topicBeta Glucan Immune Function Randomized Trial
claimFungal β-1,3-glucans are structurally conserved polysaccharide components of the fungal cell wall that exhibit potent immunomodulatory activity.
evidence level4
citationSamiksha F (2026)
sourceFungal β-1,3-glucans: Cell Wall Constituents That Promote Gut Health Through Innate Immune Modulation.
topicBeta Glucan Immune Function Randomized Trial
claimThese molecules are recognized by pattern recognition receptors, Toll-like receptors, complement receptor 3, lactosylceramide, scavenger receptors, and EphA2.
evidence level4
citationSamiksha F (2026)
sourceFungal β-1,3-glucans: Cell Wall Constituents That Promote Gut Health Through Innate Immune Modulation.