topicBeetroot Nitrate Blood Pressure Randomized Trial
claimBackground/Objectives: Health challenges associated with metabolic syndrome (MetS) have stimulated investigations into the effectiveness of nutraceutical interventions, including beetroot juice (BRJ), in mitigating MetS risk factors.
evidence level4
citationHaswell C (2026)
sourceEffects of Nitrate- and Betalain-Rich Beetroot Juice Ingestion on Vascular Function and Metabolic Syndrome Risk Factors in Healthy Adults: A Pilot Study.
topicBeetroot Nitrate Blood Pressure Randomized Trial
claimConclusions: Supplementation with BRJ reduced SBP relative to placebo, and the betalain-rich NZBR also reduced SVR, whereas the higher-nitrate UKBR did not.
evidence level4
citationHaswell C (2026)
sourceEffects of Nitrate- and Betalain-Rich Beetroot Juice Ingestion on Vascular Function and Metabolic Syndrome Risk Factors in Healthy Adults: A Pilot Study.
topicBeetroot Nitrate Blood Pressure Randomized Trial
claimMethods: This repeated-measures crossover trial ( n = 16 healthy participants) investigates the effects of daily ingestion of two different BRJs [United Kingdom beetroot juice (UKBR), 1280 mg nitrate, 147 mg betalains; New Zealand beetroot juice (NZBR), 1120 mg nitrate, 506 mg betalains] and placebo (PL) on plasma nitrate and nitrite levels, MetS biomarkers and systemic vascular resistance (SVR).
evidence level4
citationHaswell C (2026)
sourceEffects of Nitrate- and Betalain-Rich Beetroot Juice Ingestion on Vascular Function and Metabolic Syndrome Risk Factors in Healthy Adults: A Pilot Study.
topicBeetroot Nitrate Blood Pressure Randomized Trial
claimNitrate, produced endogenously, and absorbed from dietary sources (e.g., beetroot), is concentrated in/secreted by the salivary glands and reduced by lingual bacterial nitrate reductases to nitrite (the 'enterosalivary circulation').
evidence level4
citationWebb AJ (2026)
sourceLowering salivary pH with sugar-containing gum augments salivary nitrite production and blood pressure reduction with dietary nitrate (beetroot juice).
topicBeetroot Nitrate Blood Pressure Randomized Trial
claimFollowing systemic absorption, nitrite is further reduced to vasodilating NO intravascularly.
evidence level4
citationWebb AJ (2026)
sourceLowering salivary pH with sugar-containing gum augments salivary nitrite production and blood pressure reduction with dietary nitrate (beetroot juice).
topicBeetroot Nitrate Blood Pressure Randomized Trial
claimSystolic and diastolic BP were decreased by 2.7 ± 0.5 and 1.9 ± 0.5 mmHg, respectively (both p Conclusion Acutely lowering salivary pH (with sugar-containing gum) augments salivary nitrite production, plasma [nitrite] and BP-lowering with dietary nitrate.
evidence level4
citationWebb AJ (2026)
sourceLowering salivary pH with sugar-containing gum augments salivary nitrite production and blood pressure reduction with dietary nitrate (beetroot juice).
topicBeetroot Nitrate Blood Pressure Randomized Trial
claimAims The nitrate-nitrite-nitric oxide (NO) pathway has a wide range of effects including blood pressure (BP) regulation.
evidence level4
citationWebb AJ (2026)
sourceLowering salivary pH with sugar-containing gum augments salivary nitrite production and blood pressure reduction with dietary nitrate (beetroot juice).