topicAstaxanthin Skin Photoaging Randomized Trial
claimExtended exposure to solar UV radiation has been associated with a range of negative impacts on the skin, including the development of wrinkles, dryness, hyperpigmentation, thinning of the topmost layer of the skin, heightened fragility, and noticeable changes in the elastic fibers of the underlying skin layer.
evidence level1
citationYang Qifeng (2025)
sourceEffectiveness of dietary supplements for skin photoaging in healthy adults: a systematic review and meta-analysis of randomized controlled trials
topicAstaxanthin Skin Photoaging Randomized Trial
claimMoreover, UV radiation is extensively acknowledged as a prevalent environmental carcinogen, and excessive exposure is closely associated with the development of skin cancer.
evidence level1
citationYang Qifeng (2025)
sourceEffectiveness of dietary supplements for skin photoaging in healthy adults: a systematic review and meta-analysis of randomized controlled trials
topicAstaxanthin Skin Photoaging Randomized Trial
claimThe accumulating evidence strongly supports the idea that UV levels are rising due to the depletion of stratospheric ozone and the influence of climate change.
evidence level1
citationYang Qifeng (2025)
sourceEffectiveness of dietary supplements for skin photoaging in healthy adults: a systematic review and meta-analysis of randomized controlled trials
topicAstaxanthin Skin Photoaging Randomized Trial
claim1 2 3 2 4 5 7 Enhancing the skin’s softness and aesthetics is a widespread aspiration, particularly among women.
evidence level1
citationYang Qifeng (2025)
sourceEffectiveness of dietary supplements for skin photoaging in healthy adults: a systematic review and meta-analysis of randomized controlled trials
topicAstaxanthin Skin Photoaging Randomized Trial
claimAccumulation of damage leads to increased reactive oxygen species and changes the properties and quantity of matrix proteins [].
evidence level2
citationAfzal Laila (2026)
sourceProspective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging
topicAstaxanthin Skin Photoaging Randomized Trial
claimReduced collagen has been shown to contribute to skin aging and is what contributes to wrinkle formation [].
evidence level2
citationAfzal Laila (2026)
sourceProspective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging
topicAstaxanthin Skin Photoaging Randomized Trial
claimAstaxanthin (ASX) is an α‐hydroxy‐ketocarotenoid found in numerous bacterial species, microalgae, and marine animals, including shrimp, crab, and salmon [,].
evidence level2
citationAfzal Laila (2026)
sourceProspective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging
topicAstaxanthin Skin Photoaging Randomized Trial
claim1 1 2 3 4 4 3 4 Human skin is a complex organ that covers the entire human body.
evidence level2
citationAfzal Laila (2026)
sourceProspective, Randomized, Double‐Blind, Placebo‐Controlled Study of an Oral Antioxidant‐Rich Synbiotic Supplement on Skin Health and Photoaging