topicAstaxanthin Eye Fatigue Randomized Trial
claimThis systematic review aimed to evaluate randomized controlled trial (RCT) evidence on the effects of carotenoids, anthocyanins, polyunsaturated fatty acids, and combined nutraceutical formulations on refractive outcomes, axial length, macular pigment optical density (MPOD), visual function, and symptoms of visual fatigue.
evidence level1
citationMartinez-Perez C (2025)
sourceNutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.
topicAstaxanthin Eye Fatigue Randomized Trial
claimEligible studies were RCTs involving individuals with myopia or at risk of myopia, comparing nutritional supplementation with placebo or active controls.
evidence level1
citationMartinez-Perez C (2025)
sourceNutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.
topicAstaxanthin Eye Fatigue Randomized Trial
claimTwo reviewers independently screened studies, extracted data, and assessed risk of bias using the Cochrane RoB 2 tool.
evidence level1
citationMartinez-Perez C (2025)
sourceNutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.
topicAstaxanthin Eye Fatigue Randomized Trial
claimBackground/objectives Nutritional supplementation has been proposed as a potential adjunct strategy in myopia prevention and control through antioxidative, anti-inflammatory, and extracellular matrix-regulating mechanisms.
evidence level1
citationMartinez-Perez C (2025)
sourceNutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.
topicAstaxanthin Eye Fatigue Randomized Trial
claimIt is imperative to develop a sustainable food system with a reduced environmental footprint [,,].
evidence level3
citationZhang Xiaomei (2026)
sourceMicroalgae as Novel Food Resources: Technological Breakthroughs, Application Bottlenecks, and Future Pathways
topicAstaxanthin Eye Fatigue Randomized Trial
claimWe synthesize evidence on nutritional evaluation, application scenarios, and global regulatory differences, and analyze key bottlenecks.
evidence level3
citationZhang Xiaomei (2026)
sourceMicroalgae as Novel Food Resources: Technological Breakthroughs, Application Bottlenecks, and Future Pathways
topicAstaxanthin Eye Fatigue Randomized Trial
claimThese advances include improvements in cultivation systems such as closed photobioreactors and optimized open-pond systems that have enhanced biomass productivity and reduced contamination risks [].
evidence level3
citationZhang Xiaomei (2026)
sourceMicroalgae as Novel Food Resources: Technological Breakthroughs, Application Bottlenecks, and Future Pathways
topicAstaxanthin Eye Fatigue Randomized Trial
claim1 2 3 4 According to United Nations projections, the global population is expected to continue growing over the next 50–60 years, peaking at approximately 10.3 billion around the mid-2080s [].
evidence level3
citationZhang Xiaomei (2026)
sourceMicroalgae as Novel Food Resources: Technological Breakthroughs, Application Bottlenecks, and Future Pathways