topicArginine Exercise Performance Meta-Analysis
claimRisk of bias, small-study effects, sensitivity analyses, and GRADE certainty were assessed.
evidence level1
citationWang X (2026)
sourceEffects of Citrulline Malate Supplementation on Exercise Performance: A Systematic Review and Three-Level Meta-Analysis.
topicArginine Exercise Performance Meta-Analysis
claimCM supplementation was associated with a small improvement in overall exercise performance (g = 0.16, p = 0.01); however, prediction intervals were wide and statistical power was limited.
evidence level1
citationWang X (2026)
sourceEffects of Citrulline Malate Supplementation on Exercise Performance: A Systematic Review and Three-Level Meta-Analysis.
topicArginine Exercise Performance Meta-Analysis
claimCurrent evidence appeared more stable for acute than chronic supplementation, although the protocol subgroup difference remained uncertain.
evidence level1
citationWang X (2026)
sourceEffects of Citrulline Malate Supplementation on Exercise Performance: A Systematic Review and Three-Level Meta-Analysis.
topicArginine Exercise Performance Meta-Analysis
claimBackground: Citrulline malate (CM) is commonly used as an ergogenic supplement, but its effects on exercise performance and perceived exertion remain uncertain.
evidence level1
citationWang X (2026)
sourceEffects of Citrulline Malate Supplementation on Exercise Performance: A Systematic Review and Three-Level Meta-Analysis.
topicArginine Exercise Performance Meta-Analysis
claimPlateau environments are characterised by low atmospheric pressure, reduced oxygen levels, low temperatures, and high levels of ultraviolet radiation.
evidence level1
citationMa Huizi (2026)
sourceEnhancing Exercise Performance Under Hypoxia: A Network Meta-Analysis and Animal Experimental Validation of Plant Bioactive Compounds
topicArginine Exercise Performance Meta-Analysis
claimAt high altitudes, decreased atmospheric pressure and reduced environmental oxygen content lead to hypobaric hypoxia.
evidence level1
citationMa Huizi (2026)
sourceEnhancing Exercise Performance Under Hypoxia: A Network Meta-Analysis and Animal Experimental Validation of Plant Bioactive Compounds
topicArginine Exercise Performance Meta-Analysis
claimIt is influenced by multiple factors, including reduced energy substrates (glucose and glycogen levels), accumulation of metabolites (such as lactic acid and blood urea nitrogen), alterations in skeletal muscle metabolism, and changes in exercise motivation [,].
evidence level1
citationMa Huizi (2026)
sourceEnhancing Exercise Performance Under Hypoxia: A Network Meta-Analysis and Animal Experimental Validation of Plant Bioactive Compounds
topicArginine Exercise Performance Meta-Analysis
claim1 Hypoxic environments are natural or artificial settings where atmospheric oxygen levels fall below normal levels.
evidence level1
citationMa Huizi (2026)
sourceEnhancing Exercise Performance Under Hypoxia: A Network Meta-Analysis and Animal Experimental Validation of Plant Bioactive Compounds