Structured evidence table for Anserine Carnosine Cognition Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Anserine Carnosine Cognition Randomized Trial | The Cochrane Risk of Bias (ROB) 2.0 tool was used to assess the ROB in randomized controlled trials (RCTs). | 1 | Hsiao YF (2026) | The Effects of Carnosine on Cognitive Function and Mental Health-A Systematic Review and Meta-Analysis. |
| Anserine Carnosine Cognition Randomized Trial | Additionally, meta-analysis results showed that L-carnosine combined with anserine or antioxidant supplementation significantly improved the MMSE score compared to placebo (pooled net change = 0.62; 95% CI 0.23, 1.01), with small statistical heterogeneity ( I 2 = 21.3%). | 1 | Hsiao YF (2026) | The Effects of Carnosine on Cognitive Function and Mental Health-A Systematic Review and Meta-Analysis. |
| Anserine Carnosine Cognition Randomized Trial | Conclusions: A low strength of evidence suggests that L-carnosine supplement combined with anserine or antioxidants can slow cognitive function decline among healthy elderly or patients with probable Alzheimer's Disease or mild neurocognitive disorder. | 1 | Hsiao YF (2026) | The Effects of Carnosine on Cognitive Function and Mental Health-A Systematic Review and Meta-Analysis. |
| Anserine Carnosine Cognition Randomized Trial | Introduction: Previous research has shown that L-carnosine (β-alanyl-L-histidine) can reduce cognitive decline and improve mental health outcomes, but an updated systematic review of the effects of carnosine alone or in combination with other supplemental nutrients or bioactive compounds on these interconnected outcomes is lacking. | 1 | Hsiao YF (2026) | The Effects of Carnosine on Cognitive Function and Mental Health-A Systematic Review and Meta-Analysis. |
| Anserine Carnosine Cognition Randomized Trial | The four human isoforms hCA I, II, VA and IX were activated in the low to high micromolar range, with a rather complex structure activity relationship. | 4 | Vistoli G (2020) | Activation Effects of Carnosine- and Histidine-Containing Dipeptides on Human Carbonic Anhydrases: A Comprehensive Study. |
| Anserine Carnosine Cognition Randomized Trial | A performed computational study allowed us to rationalize these results and to propose a binding mode of these activators within the enzyme active site. | 4 | Vistoli G (2020) | Activation Effects of Carnosine- and Histidine-Containing Dipeptides on Human Carbonic Anhydrases: A Comprehensive Study. |
Source documents