Structured evidence table for Alpha Lipoic Acid Metabolic Health Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Alpha Lipoic Acid Metabolic Health Meta-Analysis | Advanced glycation end products (AGEs) drive metabolic dysfunction, inflammation, and age-related disease, and their accumulation accelerates after menopause. | 2 | Tanwar V (2026) | Reduction of glycation stress as a geroscience intervention: protocol for a pilot RCT in postmenopausal women. |
| Alpha Lipoic Acid Metabolic Health Meta-Analysis | Preclinical studies show that GLYLO, a five-compound glycation-lowering formulation (alpha-lipoic acid, nicotinamide, pyridoxine, benfotiamine, and piperine), reduces AGE burden and improves metabolic health, but its translational relevance in humans is unknown. | 2 | Tanwar V (2026) | Reduction of glycation stress as a geroscience intervention: protocol for a pilot RCT in postmenopausal women. |
| Alpha Lipoic Acid Metabolic Health Meta-Analysis | With the aging population in China and the continuous prevalence of metabolic risk factors, the incidence of CVDs is increasing. | 4 | Ge Liangqing (2026) | Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review) |
| Alpha Lipoic Acid Metabolic Health Meta-Analysis | Accumulating evidence demonstrates that ferroptosis is strongly associated with the initiation and progression of a wide range of diseases, including cancer, neurodegenerative disorders, immune system diseases, gastrointestinal diseases, hepatic diseases and renal diseases (–). | 4 | Ge Liangqing (2026) | Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review) |
| Alpha Lipoic Acid Metabolic Health Meta-Analysis | Morphologically, it features mitochondrial shrinkage, disappearance of mitochondrial cristae, increased mitochondrial membrane density and rupture of the outer mitochondrial membrane, while nuclear morphology remains largely unchanged (). | 4 | Ge Liangqing (2026) | Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review) |
| Alpha Lipoic Acid Metabolic Health Meta-Analysis | 1 2 2 3 4 5 6 7 8 11 Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide (). | 4 | Ge Liangqing (2026) | Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review) |
Source documents