Structured evidence table for Alpha-Lipoic Acid Cardiometabolic Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Alpha-Lipoic Acid Cardiometabolic Meta-Analysis | Experimental data and clinical studies highlight the cardiometabolic changes associated with gonadal aging and reproductive hormones’ withdrawal []. | 3 | Karaflou Maria (2026) | Antioxidants in Menopausal Transition and Male Late-Onset Hypogonadism for the Prevention of Diabetes |
| Alpha-Lipoic Acid Cardiometabolic Meta-Analysis | Body composition changes with increased fat mass and abdominal fat distribution are associated with insulin resistance and subsequent diabetes in older ages [,]. | 3 | Karaflou Maria (2026) | Antioxidants in Menopausal Transition and Male Late-Onset Hypogonadism for the Prevention of Diabetes |
| Alpha-Lipoic Acid Cardiometabolic Meta-Analysis | 5 6 7 Oxidative stress is closely associated with conditions that predispose individuals to T2DM, including obesity. | 3 | Karaflou Maria (2026) | Antioxidants in Menopausal Transition and Male Late-Onset Hypogonadism for the Prevention of Diabetes |
| Alpha-Lipoic Acid Cardiometabolic Meta-Analysis | 1 1 2 www.pubmed.gov Menopause and male late-onset hypogonadism (LOH) are well-described transitions in females and males during their lifespan. | 3 | Karaflou Maria (2026) | Antioxidants in Menopausal Transition and Male Late-Onset Hypogonadism for the Prevention of Diabetes |
| Alpha-Lipoic Acid Cardiometabolic Meta-Analysis | Methods: We conducted a narrative review to integrate current evidence on the classification, bioavailability, molecular targets, microbiota interactions, and clinical relevance of dietary BCs. | 4 | Dos Santos EA (2026) | Dietary Bioactive Compounds: Cellular Sensory Pathways, Microbial Partners, and Clinical Realities. |
| Alpha-Lipoic Acid Cardiometabolic Meta-Analysis | Across obesity, type 2 diabetes, cardiovascular disease, inflammatory bowel disease, and neurodegenerative conditions, BCs appear associated with improved inflammatory, metabolic, and redox regulation. | 4 | Dos Santos EA (2026) | Dietary Bioactive Compounds: Cellular Sensory Pathways, Microbial Partners, and Clinical Realities. |
| Alpha-Lipoic Acid Cardiometabolic Meta-Analysis | However, greater standardization in study design and longer-term human trials are needed to support robust evidence-based recommendations. | 4 | Dos Santos EA (2026) | Dietary Bioactive Compounds: Cellular Sensory Pathways, Microbial Partners, and Clinical Realities. |
| Alpha-Lipoic Acid Cardiometabolic Meta-Analysis | Background/Objectives: Dietary bioactive compounds (BCs) modulate multiple cellular pathways involved in inflammation, oxidative stress, energy metabolism, and tissue homeostasis. | 4 | Dos Santos EA (2026) | Dietary Bioactive Compounds: Cellular Sensory Pathways, Microbial Partners, and Clinical Realities. |
Source documents