topicAged Garlic Extract Blood Pressure Randomized Trial
claimBackground Aged black garlic (ABG) is rich in organosulfur compounds such as S-allyl-cysteine (SAC) and may influence lipid metabolism, although evidence from controlled trials remains limited.
evidence level2
citationSerrano JCE (2026)
sourceEffects of aged black garlic (ABG10+<sup>®</sup>) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.
topicAged Garlic Extract Blood Pressure Randomized Trial
claimIn secondary exploratory analyses of NMR-derived lipoprotein subclasses, nominally significant differences were observed: ABG was associated with a reduction in the total number of particles and HDL particles.
evidence level2
citationSerrano JCE (2026)
sourceEffects of aged black garlic (ABG10+<sup>®</sup>) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.
topicAged Garlic Extract Blood Pressure Randomized Trial
claimConclusion Low-dose ABG supplementation did not significantly modify conventional lipid markers in Grade I hypertensive individuals.
evidence level2
citationSerrano JCE (2026)
sourceEffects of aged black garlic (ABG10+<sup>®</sup>) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.
topicAged Garlic Extract Blood Pressure Randomized Trial
claimThe aim of this study was to evaluate the impact of a low-dose SAC-optimized ABG on blood lipid profiles in Grade I hypertensive individuals.
evidence level2
citationSerrano JCE (2026)
sourceEffects of aged black garlic (ABG10+<sup>®</sup>) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.
topicAged Garlic Extract Blood Pressure Randomized Trial
claimExperimental and clinical evidence suggest that reduced H₂S bioavailability contributes to hypertension and associated vascular dysfunction.
evidence level3
citationNikolov NN (2026)
sourceThe Role of Hydrogen Sulfide in the Pathophysiology and Therapeutic Modulation of Hypertension: A Scoping Review.
topicAged Garlic Extract Blood Pressure Randomized Trial
claimThis study aimed to map and synthesize the breadth of mechanistic, preclinical, and clinical evidence on the role of H₂S in the pathophysiology and therapeutic modulation of hypertension.
evidence level3
citationNikolov NN (2026)
sourceThe Role of Hydrogen Sulfide in the Pathophysiology and Therapeutic Modulation of Hypertension: A Scoping Review.
topicAged Garlic Extract Blood Pressure Randomized Trial
claimThis scoping review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guideline.
evidence level3
citationNikolov NN (2026)
sourceThe Role of Hydrogen Sulfide in the Pathophysiology and Therapeutic Modulation of Hypertension: A Scoping Review.
topicAged Garlic Extract Blood Pressure Randomized Trial
claimHydrogen sulfide (H₂S) is an endogenous gasotransmitter involved in vascular regulation, endothelial signaling, oxidative balance, and inflammatory pathways relevant to blood pressure control.
evidence level3
citationNikolov NN (2026)
sourceThe Role of Hydrogen Sulfide in the Pathophysiology and Therapeutic Modulation of Hypertension: A Scoping Review.