topicAcacia Fiber Gut Health Meta-Analysis
claimInterventions with pre- or probiotics that modify the gut microbiome have shown symptom improvement in people with psychiatric conditions, including depression and anxiety () as well as reductions in feelings of stress or improved mood in healthy individuals (;).
evidence level4
citationHogenelst Koen (2025)
sourceA prebiotic intervention improves mood in everyday life in healthy women but not in men: Exploratory results from a larger double-blind placebo controlled cross-over study
topicAcacia Fiber Gut Health Meta-Analysis
claimIn another EMA study, tryptophan supplementation in healthy individuals improved daily positive affect and reduced daily negative affect ().
evidence level4
citationHogenelst Koen (2025)
sourceA prebiotic intervention improves mood in everyday life in healthy women but not in men: Exploratory results from a larger double-blind placebo controlled cross-over study
topicAcacia Fiber Gut Health Meta-Analysis
claimGiven that attention to negative emotional information, which is often increased in people with depression (), may be beneficially altered by prebiotics (;), prebiotics may also beneficially alter another depression feature, namely affective reactivity to daily life events.
evidence level4
citationHogenelst Koen (2025)
sourceA prebiotic intervention improves mood in everyday life in healthy women but not in men: Exploratory results from a larger double-blind placebo controlled cross-over study
topicAcacia Fiber Gut Health Meta-Analysis
claimDesmedt et al., 2019 Liu et al., 2019 Berding and Cryan, 2022 Noonan et al., 2020 Desmedt et al., 2019 Zhang et al., 2020 Berding et al., 2021a Berding et al., 2021b Osadchiy et al., 2019 Spichak et al., 2021 Chakrabarti et al., 2022 The gut microbiome has an intricate relation with mental health and wellbeing (;;).
evidence level4
citationHogenelst Koen (2025)
sourceA prebiotic intervention improves mood in everyday life in healthy women but not in men: Exploratory results from a larger double-blind placebo controlled cross-over study
topicAcacia Fiber Gut Health Meta-Analysis
claimCommercial acacia gum (AG) used in this study is a premium-grade free-flowing powder.
evidence level4
citationRawi MH (2023)
sourceIdentification of acacia gum fermenting bacteria from pooled human feces using anaerobic enrichment culture.
topicAcacia Fiber Gut Health Meta-Analysis
claimIt is a gummy exudate composed of arabinogalactan branched polysaccharide, a biopolymer of arabinose and galactose.
evidence level4
citationRawi MH (2023)
sourceIdentification of acacia gum fermenting bacteria from pooled human feces using anaerobic enrichment culture.