What does the evidence say about Saffron Premenstrual Syndrome Meta-Analysis?

Updated June 2026

Quick Answer

Saffron Premenstrual Syndrome Meta-Analysis has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: However, due to some potentially significant adverse events associated with its medicinal use at higher doses or prolonged administration, clinical monitoring should be considered.

Key Takeaways

  • 01However, due to some potentially significant adverse events associated with its medicinal use at higher doses or prolonged administration, clinical monitoring should be considered. [Hasheminasab FS (2026)]
  • 02Background Crocus sativus L., commonly known as saffron, is a widely used spice with a rich history of culinary and medicinal applications. [Hasheminasab FS (2026)]
  • 03This systematic review aims to compile human data from studies on monopreparations of C. [Hasheminasab FS (2026)]
  • 04A Swiss study found that 10% of participants experienced PMS, whereas 3% experienced PMDD. [Mohammadi Mohammad Mehdi (2026)]
The current Migaku evidence database contains 2 reusable source documents for Saffron Premenstrual Syndrome Meta-Analysis. This answer focuses on benefits, uncertainty, and practical interpretation. - However, due to some potentially significant adverse events associated with its medicinal use at higher doses or prolonged administration, clinical monitoring should be considered. [Hasheminasab FS (2026); evidence level 1] - Background Crocus sativus L., commonly known as saffron, is a widely used spice with a rich history of culinary and medicinal applications. [Hasheminasab FS (2026); evidence level 1] - This systematic review aims to compile human data from studies on monopreparations of C. [Hasheminasab FS (2026); evidence level 1] - A Swiss study found that 10% of participants experienced PMS, whereas 3% experienced PMDD. [Mohammadi Mohammad Mehdi (2026); evidence level 1] - These challenges include legal issues, suicidal ideation, reduced work productivity, social isolation, parenting difficulties, increased absenteeism, disruptions of personal and social relationships, and frequent hospital visits. [Mohammadi Mohammad Mehdi (2026); evidence level 1] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Adverse Events of Saffron (<i>Crocus sativus</i> L.): Systematic Review of Current Evidence.
  2. Effect of saffron on premenstrual syndrome and dysmenorrhea: a systematic review and meta-analysis