Is Rooibos Cardiometabolic Randomized Trial safe?

Updated October 2026

Quick Answer

Rooibos Cardiometabolic Randomized Trial has evidence relevant to safety, limits, and clinician-discussion contexts, but conclusions should stay close to the cited sources. One representative finding is: Elderly patients and patients with comorbidity disorders including pulmonary disease, cardiac disease, kidney disease, diabetes, and hypertension have been associated with greater mortality rates, suggesting highly susceptible and/or vulnerable groups within the infected population (,).

Key Takeaways

  • 01Elderly patients and patients with comorbidity disorders including pulmonary disease, cardiac disease, kidney disease, diabetes, and hypertension have been associated with greater mortality rates, suggesting highly susceptible and/or vulnerable groups within the infected population (,). [Sheik Abdul Naeem (2021)]
  • 02Consequently, it had been hypothesised that diabetes and hypertension treatment with ACE2-stimulating drugs increases the risk of developing severe and fatal COVID-19 (,). [Sheik Abdul Naeem (2021)]
  • 03Furthermore, there is some evidence to demonstrate that treatment with ACEIs or ARBs can decrease the severity of pulmonary injury by SARS-CoV-2, with preclinical data suggesting a potential mechanism of benefit (). [Sheik Abdul Naeem (2021)]
  • 04Lewnard and Lo, 2020 Fang et al., 2020 Emanuel et al., 2020 Shi et al., 2020 Patel and Verma, 2020 Rodriguez-Morales et al., 2020 The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the current Coronavirus disease 2019 (COVID-19) pandemic. [Sheik Abdul Naeem (2021)]
The current Migaku evidence database contains 1 reusable source document for Rooibos Cardiometabolic Randomized Trial. This answer focuses on safety, limits, and clinician-discussion contexts. - Elderly patients and patients with comorbidity disorders including pulmonary disease, cardiac disease, kidney disease, diabetes, and hypertension have been associated with greater mortality rates, suggesting highly susceptible and/or vulnerable groups within the infected population (,). [Sheik Abdul Naeem (2021); evidence level 3] - Consequently, it had been hypothesised that diabetes and hypertension treatment with ACE2-stimulating drugs increases the risk of developing severe and fatal COVID-19 (,). [Sheik Abdul Naeem (2021); evidence level 3] - Furthermore, there is some evidence to demonstrate that treatment with ACEIs or ARBs can decrease the severity of pulmonary injury by SARS-CoV-2, with preclinical data suggesting a potential mechanism of benefit (). [Sheik Abdul Naeem (2021); evidence level 3] - Lewnard and Lo, 2020 Fang et al., 2020 Emanuel et al., 2020 Shi et al., 2020 Patel and Verma, 2020 Rodriguez-Morales et al., 2020 The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the current Coronavirus disease 2019 (COVID-19) pandemic. [Sheik Abdul Naeem (2021); evidence level 3] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Rooibos, a supportive role to play during the COVID-19 pandemic?