Does Phosphatidylserine Cognitive Stress Randomized Trial work?

Updated October 2026

Quick Answer

Phosphatidylserine Cognitive Stress Randomized Trial has evidence relevant to strength of evidence and what the studies can or cannot prove, but conclusions should stay close to the cited sources. One representative finding is: Conclusions Under the present 14-day experimental conditions, the multi-ingredient protocols containing taurine, caffeine, and phosphatidylserine were associated with more favorable selected cognitive and psychomotor outcomes, 30 m sprint performance, and baseline-adjusted GPS-derived locomotor outcomes than placebo.

Key Takeaways

  • 01Conclusions Under the present 14-day experimental conditions, the multi-ingredient protocols containing taurine, caffeine, and phosphatidylserine were associated with more favorable selected cognitive and psychomotor outcomes, 30 m sprint performance, and baseline-adjusted GPS-derived locomotor outcomes than placebo. [Mizera K (2026)]
  • 02Background/objectives Cognitive fatigue and impaired psychomotor function may contribute to reductions in football-specific performance during prolonged match-like activity. [Mizera K (2026)]
  • 03This study evaluated cognitive, psychomotor, sprint, and football-specific locomotor responses to multi-ingredient protocols containing taurine, caffeine, and either 300 or 600 mg·day -1 of phosphatidylserine in professional male football players. [Mizera K (2026)]
  • 04The second study confirmed the GBP benefits on mood states and a visually consistent downward trend in reaction times across all four cognitive performance tests at both GBP dosages, suggesting improved processing speed in response to various stimuli. [Hawkins K (2026)]
The current Migaku evidence database contains 2 reusable source documents for Phosphatidylserine Cognitive Stress Randomized Trial. This answer focuses on strength of evidence and what the studies can or cannot prove. - Conclusions Under the present 14-day experimental conditions, the multi-ingredient protocols containing taurine, caffeine, and phosphatidylserine were associated with more favorable selected cognitive and psychomotor outcomes, 30 m sprint performance, and baseline-adjusted GPS-derived locomotor outcomes than placebo. [Mizera K (2026); evidence level 2] - Background/objectives Cognitive fatigue and impaired psychomotor function may contribute to reductions in football-specific performance during prolonged match-like activity. [Mizera K (2026); evidence level 2] - This study evaluated cognitive, psychomotor, sprint, and football-specific locomotor responses to multi-ingredient protocols containing taurine, caffeine, and either 300 or 600 mg·day -1 of phosphatidylserine in professional male football players. [Mizera K (2026); evidence level 2] - The second study confirmed the GBP benefits on mood states and a visually consistent downward trend in reaction times across all four cognitive performance tests at both GBP dosages, suggesting improved processing speed in response to various stimuli. [Hawkins K (2026); evidence level 2] - Mental health is threatened every day by the stressors of life: frenetic work rhythms, stressful conditions can generate anxiety, depression, cognition, and sleep problems. [Hawkins K (2026); evidence level 2] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Football-Specific Performance and Cognitive Fatigue Resistance Following Supplementation with Two Phosphatidylserine Doses Combined with Taurine and Caffeine in Professional Male Football Players: A Randomized, Triple-Masked, Placebo-Controlled Trial.
  2. Health Benefits of a Standardized <i>Ginkgo biloba</i> Extract Associated With Phosphatidylserine in Alleviating Mental Stress and Cognitive Performance: Results From Two Exploratory Randomized Trials.