Quick Answer
L-Citrulline Exercise Recovery Randomized Trial has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: For example, citrulline supplementation has been reported to improve cycling time-trial performance and oxygen uptake kinetics [,], while acute CM ingestion has also been associated with improved resistance exercise performance and reduced ratings of perceived exertion (RPE) [,].
Key Takeaways
- 01For example, citrulline supplementation has been reported to improve cycling time-trial performance and oxygen uptake kinetics [,], while acute CM ingestion has also been associated with improved resistance exercise performance and reduced ratings of perceived exertion (RPE) [,]. [Yamanaka Ryo (2026)]
- 02For example, creatine-based supplementation has improved repeated sprint performance in some treadmill- and field-based protocols [,], whereas interventions targeting related nitric oxide pathways do not necessarily enhance anaerobic performance in trained athletes []. [Yamanaka Ryo (2026)]
- 03However, evidence regarding the effects of CM on true maximal sprint performance remains limited. [Yamanaka Ryo (2026)]
- 041 2 Short-distance sprint performance is influenced by both energetic and intramuscular factors. [Yamanaka Ryo (2026)]
The current Migaku evidence database contains 2 reusable source documents for L-Citrulline Exercise Recovery Randomized Trial. This answer focuses on benefits, uncertainty, and practical interpretation.
- For example, citrulline supplementation has been reported to improve cycling time-trial performance and oxygen uptake kinetics [,], while acute CM ingestion has also been associated with improved resistance exercise performance and reduced ratings of perceived exertion (RPE) [,]. [Yamanaka Ryo (2026); evidence level 2]
- For example, creatine-based supplementation has improved repeated sprint performance in some treadmill- and field-based protocols [,], whereas interventions targeting related nitric oxide pathways do not necessarily enhance anaerobic performance in trained athletes []. [Yamanaka Ryo (2026); evidence level 2]
- However, evidence regarding the effects of CM on true maximal sprint performance remains limited. [Yamanaka Ryo (2026); evidence level 2]
- 1 2 Short-distance sprint performance is influenced by both energetic and intramuscular factors. [Yamanaka Ryo (2026); evidence level 2]
- Individual exercise tolerance is defined as the amount of physical exertion that can be sustained before task disengagement and can be increased through appropriate training strategies [,]. [Strasser Barbara (2026); evidence level 4]
Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording.
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