What does the evidence say about Garlic Cholesterol Randomized Trial?

Updated May 2026

Quick Answer

Garlic Cholesterol Randomized Trial has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: Also, total cholesterol (TC) was significantly reduced (WMD: -8.26; 95% CI: -14.65 to -1.88; I ² = 90.9%) based on 7 effect sizes, while changes in HDL-C, TG, and LDL-C were not significant overall.

Key Takeaways

  • 01Also, total cholesterol (TC) was significantly reduced (WMD: -8.26; 95% CI: -14.65 to -1.88; I ² = 90.9%) based on 7 effect sizes, while changes in HDL-C, TG, and LDL-C were not significant overall. [Ebrahimzadeh A (2026)]
  • 02Moreover, longer duration of garlic supplementation significantly improved all lipid profiles in patients with T2DM. [Ebrahimzadeh A (2026)]
  • 03Background Garlic, as an additive, a spice, and an ancient herbal medicine, has been proposed as a potential treatment for type 2 diabetes mellitus (T2DM). [Ebrahimzadeh A (2026)]
  • 04This systematic review and meta-analysis provides a comprehensive evaluation of the effects of garlic supplementation on fasting blood sugar (FBS), hemoglobin A1c (HbA1c), and lipid profile in patients with T2DM. [Ebrahimzadeh A (2026)]
The current Migaku evidence database contains 2 reusable source documents for Garlic Cholesterol Randomized Trial. This answer focuses on benefits, uncertainty, and practical interpretation. - Also, total cholesterol (TC) was significantly reduced (WMD: -8.26; 95% CI: -14.65 to -1.88; I ² = 90.9%) based on 7 effect sizes, while changes in HDL-C, TG, and LDL-C were not significant overall. [Ebrahimzadeh A (2026); evidence level 1] - Moreover, longer duration of garlic supplementation significantly improved all lipid profiles in patients with T2DM. [Ebrahimzadeh A (2026); evidence level 1] - Background Garlic, as an additive, a spice, and an ancient herbal medicine, has been proposed as a potential treatment for type 2 diabetes mellitus (T2DM). [Ebrahimzadeh A (2026); evidence level 1] - This systematic review and meta-analysis provides a comprehensive evaluation of the effects of garlic supplementation on fasting blood sugar (FBS), hemoglobin A1c (HbA1c), and lipid profile in patients with T2DM. [Ebrahimzadeh A (2026); evidence level 1] - Background Hypercholesterolemia is a significant risk factor for cardiovascular diseases, necessitating effective management strategies. [Aravind A (2025); evidence level 1] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. The Therapeutic Effect of Garlic Supplements on the Metabolic Profile of Patients With Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
  2. Effectiveness of Herbal Interventions in the Management of Hypercholesterolemia: Protocol for a Systematic Review.