What does the evidence say about Creatine and Resistance Training?

Updated August 2026

Quick Answer

Creatine and Resistance Training has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: These studies have been removed, and the affected PRISMA flow diagram, study-characteristics table, risk-of-bias summary, outcome analyses, subgroup analyses, GRADE table, figures, and supplementary files have been updated accordingly.

Key Takeaways

  • 01These studies have been removed, and the affected PRISMA flow diagram, study-characteristics table, risk-of-bias summary, outcome analyses, subgroup analyses, GRADE table, figures, and supplementary files have been updated accordingly. [Gu Jinfa (2026)]
  • 02Theandsections of the abstract have been corrected to read: This systematic review and meta-analysis pooled RCT evidence in healthy men aged 18–30 years old to quantify the effects of creatine supplementation in terms of body composition, maximal strength, and exercise performance. [Gu Jinfa (2026)]
  • 03Wingate peak and mean power both increased in both contexts (peak power +71.27 W; mean power +39.69 W), with no evidence that training context modified these results. [Gu Jinfa (2026)]
  • 04In the published article, two studies (Ostojic et al., 2004 and Percário et al., 2012) were inadvertently included despite having participants outside the prespecified eligible age range of 18–30 years. [Gu Jinfa (2026)]
The current Migaku evidence database contains 4 reusable source documents for Creatine and Resistance Training. This answer focuses on benefits, uncertainty, and practical interpretation. - These studies have been removed, and the affected PRISMA flow diagram, study-characteristics table, risk-of-bias summary, outcome analyses, subgroup analyses, GRADE table, figures, and supplementary files have been updated accordingly. [Gu Jinfa (2026); evidence level 1] - Theandsections of the abstract have been corrected to read: This systematic review and meta-analysis pooled RCT evidence in healthy men aged 18–30 years old to quantify the effects of creatine supplementation in terms of body composition, maximal strength, and exercise performance. [Gu Jinfa (2026); evidence level 1] - Wingate peak and mean power both increased in both contexts (peak power +71.27 W; mean power +39.69 W), with no evidence that training context modified these results. [Gu Jinfa (2026); evidence level 1] - In the published article, two studies (Ostojic et al., 2004 and Percário et al., 2012) were inadvertently included despite having participants outside the prespecified eligible age range of 18–30 years. [Gu Jinfa (2026); evidence level 1] - The scientific community has responded with growing scrutiny of extraordinary health and weight-loss promises that lack robust evidence, reinforcing the need for critical appraisal and public clarification regarding risks and benefits (). [Gimenez Fabiana V. M. (2026); evidence level 1] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Correction: Creatine supplementation in young men under resistance versus non-resistance training: a systematic review and meta-analysis of strength, performance, and lean mass
  2. Does creatine affect lipid profile? a systematic review and meta-analysis of randomized placebo-controlled trials
  3. Creatine supplementation in young men under resistance versus non-resistance training: a systematic review and meta-analysis of strength, performance, and lean mass
  4. Acute Creatine Ingestion Before Resistance Training Enhances Strength Performance More than Ingestion During or After Training: A Randomized Crossover Pilot Trial