What does the evidence say about Bergamot Supplementation Lipid Profile Meta-Analysis?

The current Migaku evidence database contains 2 reusable source documents for Bergamot Supplementation Lipid Profile Meta-Analysis. This answer focuses on benefits, uncertainty, and practical interpretation. - Data extraction focused on weight loss, body mass index, waist circumference, waist-to-hip ratio, and body fat percentage, and the risk of bias was assessed using the Revised Cochrane Risk-of-Bias Tool. [Pujia C (2026); evidence level 1] - This systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to assess the effect of nutraceuticals containing Citrus bergamia on the management of obesity in adults by assessing measures related to obesity. [Pujia C (2026); evidence level 1] - We searched the following databases until October 2024: PubMed, Web of Science, Scopus, and the Cochrane Central Register of Controlled Trials. [Pujia C (2026); evidence level 1] - 7 8 9 10 11 In addition to its essential oil, bergamot is a relevant source of polyphenols and flavonoids, including unique C-glycosyl flavonoids such as brutieridin and melitidin [], which have been associated with cardiometabolic, antioxidant, and anti-inflammatory effects [,,,]. [De Bruno Alessandra (2026); evidence level 3] - Currently, most industrial residues are mainly destined for livestock feed or bioenergy production, despite evidence showing that bergamot pomace and peel-derived fractions exhibit high phenolic content and strong antioxidant activity, as assessed by commonly used spectrophotometric assays such as DPPH, ABTS, and FRAP [,,]. [De Bruno Alessandra (2026); evidence level 3] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.