Does Bergamot Lipids Randomized Trial work?

Updated October 2026

Quick Answer

Bergamot Lipids Randomized Trial has evidence relevant to strength of evidence and what the studies can or cannot prove, but conclusions should stay close to the cited sources. One representative finding is: Introduction Bergamot and opuntia (prickly pear cladodes) standardized extracts have been demonstrated to have positive metabolic effects in preclinical and clinical models.

Key Takeaways

  • 01Introduction Bergamot and opuntia (prickly pear cladodes) standardized extracts have been demonstrated to have positive metabolic effects in preclinical and clinical models. [Fogacci F (2022)]
  • 02Material and methods The aim of this study was to evaluate the metabolic effect of a combined nutraceutical containing 150 mg of Opuntia ficus Indica extract, 400 mg of plant sterols, 12.5 mg of thiamine, and 200 mg of Brumex ® a phytocomplex from bergamot fruit ( Citrus bergamia Risso et Poiteau, fructus) standardized 40% in total flavonoids and min 5% in 3-hydroxy-3-methylglutaryl-flavanones. [Fogacci F (2022)]
  • 03Introduction: Aging is a process characterised by a decline in physiological functions. [Remigante A (2023)]
  • 04Due to the close relationship between aging and oxidative stress, functional foods rich in phytochemicals are excellent candidates to neutralise age-related changes. [Remigante A (2023)]
The current Migaku evidence database contains 2 reusable source documents for Bergamot Lipids Randomized Trial. This answer focuses on strength of evidence and what the studies can or cannot prove. - Introduction Bergamot and opuntia (prickly pear cladodes) standardized extracts have been demonstrated to have positive metabolic effects in preclinical and clinical models. [Fogacci F (2022); evidence level 2] - Material and methods The aim of this study was to evaluate the metabolic effect of a combined nutraceutical containing 150 mg of Opuntia ficus Indica extract, 400 mg of plant sterols, 12.5 mg of thiamine, and 200 mg of Brumex ® a phytocomplex from bergamot fruit ( Citrus bergamia Risso et Poiteau, fructus) standardized 40% in total flavonoids and min 5% in 3-hydroxy-3-methylglutaryl-flavanones. [Fogacci F (2022); evidence level 2] - Introduction: Aging is a process characterised by a decline in physiological functions. [Remigante A (2023); evidence level 4] - Due to the close relationship between aging and oxidative stress, functional foods rich in phytochemicals are excellent candidates to neutralise age-related changes. [Remigante A (2023); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Comparative effect of a nutraceutical compound based on a flavonoid complex from bergamot on plasma lipids, glucose metabolism, and liver enzymes: a 3-arm, double-blind, placebo-controlled, randomized clinical trial.
  2. Mechanisms underlying the anti-aging activity of bergamot (<i>Citrus bergamia</i>) extract in human red blood cells.