# Vitamin D Mood Randomized Trial: What the Evidence Says
Canonical: https://www.migaku.app/guides/vitamin-d-mood-randomized-trial-evidence-review
Category: evidence-review
Summary: Vitamin D Mood Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are mixed b
Last reviewed: 2026-06-24
Reviewed by: Migaku Evidence Review
# Vitamin D Mood Randomized Trial: What the Evidence Says

## Quick Answer

Vitamin D Mood Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are mixed biomedical and public-health sources, so conclusions should be framed as evidence-aware guidance rather than medical advice.

## Key Takeaways

- This page is generated only from sources stored in the Migaku evidence knowledge base.
- Current evidence mix: 1 preclinical study, 1 research article.
- Claims should be interpreted with the source type, study design, population, and publication date in mind.
- This article is educational and does not replace care from a qualified clinician.

## Evidence Map

| Source | Evidence type | Level | Date | Identifier |
| --- | --- | ---: | --- | --- |
| Brain Foods: A Narrative Review of Food Items and Their Impact on Cognition over the Life Course. | preclinical study | 4 | 2026-05-31 | 10.3390/nu18111779 |
| Effect of vitamin D supplementation on fatigue and mood among perimenopausal women | research article | 4 | 2026-01-01 | 10.6026/973206300221638 |

## What The Sources Report

- This review synthesizes current evidence on the effects of both plant- and animal-derived foods on cognitive outcomes from early development through older adulthood. [Hardaway C (2026); evidence level 4]
- Evidence was evaluated across life stages, considering nutrient bioavailability, dietary patterns, and the interplay between structural, socioeconomic, and environmental factors that influence access to these foods. [Hardaway C (2026); evidence level 4]
- These manifestations not only affect daily functioning and productivity but also
contribute to long-term health consequences, including reduced social engagement, impaired occupational performance and increased healthcare
utilization. [Ray Prama (2026); evidence level 4]
- Although these symptoms are often attributed solely to
hormonal shifts, emerging evidence suggests that nutritional deficiencies may play a significant and potentially modifiable role in the
pathophysiology of perimenopausal fatigue and mood disorders. [Ray Prama (2026); evidence level 4]

## How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

## Practical Interpretation

For vitamin D mood randomized trial, the current source set is useful for orientation, but it is not yet broad enough for strong claims. Use cautious language and keep conclusions close to the cited sources.

## Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

## References

- Hardaway C (2026). Brain Foods: A Narrative Review of Food Items and Their Impact on Cognition over the Life Course.. DOI: 10.3390/nu18111779. PMCID: PMC13258466. PMID: 42280422. https://pmc.ncbi.nlm.nih.gov/articles/PMC13258466/
- Ray Prama (2026). Effect of vitamin D supplementation on fatigue and mood among perimenopausal women. DOI: 10.6026/973206300221638. PMCID: PMC13177140. PMID: 42145430. License: https://creativecommons.org/licenses/by/3.0/. https://pmc.ncbi.nlm.nih.gov/articles/PMC13177140/

## Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.