# Vitamin D Mood Meta-analysis: What the Evidence Says
Canonical: https://www.migaku.app/guides/vitamin-d-mood-meta-analysis-evidence-review
Category: evidence-review
Summary: Vitamin D Mood Meta-analysis has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systematic
Last reviewed: 2026-05-28
Reviewed by: Migaku Evidence Review
# Vitamin D Mood Meta-analysis: What the Evidence Says

## Quick Answer

Vitamin D Mood Meta-analysis has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systematic review, so conclusions should be framed as evidence-aware guidance rather than medical advice.

## Key Takeaways

- This page is generated only from sources stored in the Migaku evidence knowledge base.
- Current evidence mix: 1 systematic review, 1 research article.
- Claims should be interpreted with the source type, study design, population, and publication date in mind.
- This article is educational and does not replace care from a qualified clinician.

## Evidence Map

| Source | Evidence type | Level | Date | Identifier |
| --- | --- | ---: | --- | --- |
| A systematic review and meta-analysis of randomized controlled trials investigated the effects of melatonin supplementation on bone mineral density, quality of life, and sleep in menopausal women | systematic review | 1 | 2026-01-29 | 10.3389/fnut.2026.1687221 |
| Vitamin E Intake Modulates the Effect of Selenomethionine on Sexual Function and Depressive Symptoms in Reproductive-Age Women with Euthyroid Autoimmune Thyroiditis: A Pilot Study | research article | 4 | 2026-04-26 | 10.3390/antiox15050549 |

## What The Sources Report

- Additionally, we recorded the specific time points at which outcomes were measured, such as the conclusion of treatment or particular follow-up visits. [Du Ji (2026); evidence level 1]
- To reduce potential bias, two researchers independently conducted the literature review, selected articles, extracted data, and assessed the risk of bias. [Du Ji (2026); evidence level 1]
- Furthermore, euthyroid Hashimoto's thyroiditis may be followed by insulin resistance, metabolic syndrome, increased cardiovascular risk, and impaired cognitive function. [Krysiak Robert (2026); evidence level 4]

## How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

## Practical Interpretation

There is at least one systematic-review style source in the current set, so it deserves more weight than single-study evidence. For vitamin d mood meta-analysis, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

## Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

## References

- Du Ji (2026). A systematic review and meta-analysis of randomized controlled trials investigated the effects of melatonin supplementation on bone mineral density, quality of life, and sleep in menopausal women. DOI: 10.3389/fnut.2026.1687221. PMCID: PMC12894000. PMID: 41693954. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC12894000/
- Krysiak Robert (2026). Vitamin E Intake Modulates the Effect of Selenomethionine on Sexual Function and Depressive Symptoms in Reproductive-Age Women with Euthyroid Autoimmune Thyroiditis: A Pilot Study. DOI: 10.3390/antiox15050549. PMCID: PMC13203289. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13203289/

## Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.